Title: A Study to Assess Correlation of Adenosine Deaminase Activity with Different Predictors and Parameters of Diabetes and Obesity
Authors: Vivek Sharma, Arun Mishra, Dr Neeraj Gour, Dr Poornima Dey Sarkar
DOI: https://dx.doi.org/10.18535/jmscr/v5i12.16
Abstract
Introduction: Obesity is a complex disorder that involves some degree of over-consumption1 coupled with a metabolic derangement. As ADA has been putatively associated with inflammation, and adipose tissue inflammation is the hallmark of insulin resistance in obese T2DM patients. Our study attempted to evaluate the role of serum ADA in T2DM subjects.
Methods: This observational cross sectional study was conducted in the Department of Biochemistry at MGM Medical College and MY Hospital. All the patients and controls were clinically examined and routine biochemical tests were analyzed for all subjects.
Result: Correlations of ADA with different predictors of obesity and diabetes were calculated. ADA was found to be positively correlated with FBS, HBA1C, Insulin, Leptin and HOMA IR whereas negative correlation was found between ADA and Adiponectin.
Conclusion: This is very much evident through this study that ADA may be treated as prognostic predictor of diabetes either linked to obesity or not.
Keywords: ADA; Diabetes; Obesity.
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