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Category: Volume 05 Issue 11 November 2017
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Title: A Study on the Correlation of Serum uric acid and Dyslipidemia with Glycaemic Status in Type 2 Diabetes Mellitus

Authors: Md Tanweer Ushmani, Rajiv Ranjan, Kumari Tanuja

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i11.191

Abstract

Objectives: Our study was to detect the correlation of serum uric acid level with glycaemic status and with lipid profile. And also evaluate the various biochemical parameters, anthropometric measurements, blood pressure, serum uric acid level and associated factors.

Methodology: A 100 subjects with type 2 diabetes mellitus as a case and 100 subjects with non diabetics as control with age group greater than 40 years were enrolled in this study. A detail history, dietary pattern, clinical examination and relevant investigation were performed. Anthropometric examination like as measurement of BMI, measurement of waist-hip ratio and biochemical investigations like as blood glucose, Serum HbA1C estimation, Serum uric acid and Serum lipid profile were performed to all subjects.

Results: Data was analyzed by using SPSS software (Version 17). Mean ± SD was observed.  One way analysis of variance (ANOVA) with post hock analysis using Tukey’s multiple comparison test and Pearson correlation coefficient (r) was applied. P value was taken ≤ 0.05 for significant differences.

Conclusions: Type 2 diabetes mellitus patients is a strong negative correlation between blood glucose level and serum uric acid level. So that serum uric acid can be used as an important parameter to assess future cardiovascular risk in a type2 diabetes mellitus patient.

Keywords: Type 2 diabetes mellitus, anthropometric examination, Serum uric acid, serum lipid profile

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Corresponding Author

Dr Md Tanweer Ushmani

Assistant Professor, Department of Physiology,

Katihar Medical College, Katihar, Bihar, India

Ph: +91 8521667405