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Category: Volume 05 Issue 11 November 2017
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Title: Evaluation of Left Ventricular Diastolic Dysfunction in Patients with Coronary Artery Disease: Correlation between Echocardiographic and Hemodynamic Parameters

Authors: Kushaal Vikram, Lipika Adhikari, Biswajit Majumder, S Paul Chowdhury, Pritam Kr Chatterjee

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i11.57

Abstract

In patients with coronary heart disease, evaluation of the left ventricular end diastolic pressure (LVEDP) provides assessment of the hemodynamic severity and aids in assessing the prognosis, and in deciding the proper management and therapeutic interventions. It also helps to distinguish this syndrome from other diseases such as pulmonary disease that can result in dyspnoea.

The early diastolic doppler indexes derived from transmitral flow velocity curves correlated significantly with LV filling pressures in patients with systolic dysfunction, but the correlation was weak in patients with preserved systolic function. The difference between the pulmonary venous and mitral A durations correlated well with LVEDP in patients with CAD, irrespective of the systolic function.

In this study we found echocardiographic doppler derived transmitral and pulmonary venous flow indices can be used as a safe and noninvasive means of predicting the LV filling pressures in patients with coronary artery disease, especially in patients with LV systolic dysfunction, as an alternative to the invasive measurements obtained during cardiac catheterization.

Keywords: Coronary artery Disease (CAD), Left ventricular Ejection Fraction (LVEF), Left ventricular end diastolic pressure (LVEDP), Echo Doppler parameter.

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Corresponding Author

Lipika Adhikary

Assistant Professor, Cardiology Department, R.G Kar Hospital, Kolkata

Address: C/O Manoj Adhikary, Schooldanga, Bankura, West Bengal, India, Pin- 722101