Title: Prevalence of Hyponatremia among patients admitted with Cirrhosis Liver and its Correlation with Hepatic Encephalopathy
Authors: Dr Prasanna Kumari K, Dr Udayamma KP
DOI: https://dx.doi.org/10.18535/jmscr/v5i11.33
Abstract
Hyponatremia is an electrolyte imbalance encountered in patients with end-stage liver disease. It occur in about 57% of hospitalized patients with cirrhosis. Hyponatremia in cirrhosis is an independent risk factor for mortality and is common in patients with end-stage liver disease. These patients had a significantly higher incidence of hepatic encephalopathy, hepatorenal syndrome, and spontaneous bacterial peritonitis. Hepatic encephalopathy is worsened by the presence of hyponatremia. Hyponatremia can induce or aggravate HE, leading to disease progression and even death.
Aim: To study the Prevalence of Hyponatremia among Patients admitted with Cirrhosis liver and its correlation with Hepatic Encephalopathy.
Materials and Methods: It is an observational Study of one year duration conducted among 120 patients with cirrhosis admitted in General Medicine and Medical Gastroenterology in a tertiary care centre in south kerala. Data collected and analyzed using SPSS Software.
Conclusions: Among the 120 cases enrolled in the study, majority were males. 36 % of the patients belonged to age group 51 -60 years with mean age 53.28 (SD -9.64).The prevalence of hyponatremia was 59% .There is a positive correlation between hyponatremia and hepatic encephalopathy.(p value 0.001). More patients with severe hyponatremia belonged to Child- Pugh class C. The patients with hyponatremia and hepatic encephalopathy had poor prognosis.
Keywords: Hyponatremia; Cirrhosis, Hepatic encephalopathy, Prevalence.
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