Details
Category: Volume 05 Issue 10 October 2017
Hits: 1374

Title: Sarcoma in Head and Neck: A Study of 25 Cases in Regional Cancer Centre

Authors: Rajjyoti Das, Kunal Ranjan, Sudhakar GVS, Anil Kareth Mathew, Amal Chandra Katak

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i10.190

Abstract

Soft tissue sarcomas are rare tumours that account for less than 1% of all malignancies. Histopathologically diagnosed cases at Regional Cancer Centre (RCC) BBCI Guwahati between July 2010 and December 2016 were analyzed retrospectively. A total of 25 cases were seen during the study period. The mandible, tongue, orbit, scalp and maxilla were the commonest sites affected. None of the patients had neck nodes or distant metastasis at presentation.18 patients were treated with surgical resection primarly and this was followed by adjuvant treatment. The majority of the patients failed within first and second year. Grade of tumour and T stage of the tumor were found to have a significant effect on prognosis.

Keywords:  Head and neck, sarcoma, lung metastasis, radiotherapy, chemotherapy, VAC.

References

  1. Gorsky M, Epstein JB. Craniofacial osseous and chondromatous sarcomas in British Columbia, a review of 34 cases. Oral Oncol. 2000;36:27–31. doi: 10.1016/S1368-8375(99)00042-1. 
  2. Sturgis EM, Potter BO. Sarcomas of the head and neck region. Curr Opin Oncol. 2003;15:239–252. doi: 10.1097/00001622-200305000-00011.
  3. Kraus DH, Dubner S, Harrison LB, et al. Prognostic factors for recurrence and survival in head and neck soft tissue sarcomas. 1994;74:697–702.doi:10.1002/1097-0142(19940715)74:2<697::AID-CNCR2820740224>3.0.CO;2-A
  4. M. Mendenhall, C. M. Mendenhall, J. W. Werning, C. E. Riggs, and N. P. Mendenhall, “Adult head and neck soft tissue sarcomas,” Head & Neck, vol. 27, no. 10, pp. 916–922, 2005
  5. Parsons, R. A. Zlotecki, K. A. Reddy, T. P. Mitchell, R. B. Marcus Jr., and M. T. Scarborough, “The role of radiotherapy and limb-conserving surgery in the management of soft-tissue sarcomas in adults,”.
  6. O'Sullivan, P. Gullane, J. Irish et al., “Preoperative radiotherapy for adult head and neck soft tissue sarcoma: assessment of wound complication rates and cancer outcome in a prospective series,” World Journal of Surgery, vol. 27, no. 7, pp. 875–883, 2003
  7. L. Barker Jr., A. C. Paulino, S. Feeney, T. McCulloch, and H. Hoffman, “Locoregional treatment for adult soft tissue sarcomas of the head and neck: an institutional review,” Cancer, vol. 9, no. 1, pp. 49–57, 2003.
  8. Guadagnolo, B.A.; Zagars, G.K.; Raymond, A.K.; Benjamin, R.S.; Sturgis, E.M. Osteosarcoma of the jaw/craniofacial region outcomes after multimodality treatment. Cancer 2009, 115, 3262–3270
  9. Nasri S, Mark RJ, Sercarz JA, Tran LM, Sadeghi S. Pediatric Sarcomas of the Head and Neck Other Than Rhabdomyos-arcoma. Am J Otolaryngol.1995;3:165-71
  10. Kraus DH, Dubner S, Harrison LB, et al. Prognostic factors for recurrence and survival in head and neck soft tissue sarcomas. 1994;74:697–702.doi:10.1002/1097-0142(19940715)74:2<697::AID-CNCR2820740224>3.0.CO;2-A
  11. Sturgis EM, Potter BO. Sarcoma of the head and neck. Curr Opinion Oncol. 2003;15:239-52.

Corresponding Author

Kunal Ranjan

MS ENT, Fellow Department of Head and Neck Oncology BBCI,

(Dr. Bhubaneswar Borooah Cancer Institute, Guwahati - 781 016)

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.