Title: Aetiological Spectrum of Chronic Suppurative Otitis Media in a Tertiary Care Centre in Kerala

Authors: Dr Jyothi.R, Dr Samitha, Dr Harilal, Dr Ramani Bai.J.T, Dr Lancy.J

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i10.188

Abstract

Chronic suppurative otitis media (CSOM) is characterized by persistent purulent discharge from the ear which causes hearing loss in the later stages. This condition occurs as asequelae to inadequately treated acute otitis media causing persistent perforation in the tympanic membrane which could be infected from bacteria in the external auditory canal. Several studies have been done regarding the microbial aetiology of CSOM with widely varying results.

A study was conducted in the Department of Microbiology, Govt. Medical College, Thiruvananthapuram, Kerala with the objective of profiling the aetiological spectrum of CSOM and using this information to formulate an ideal antibiotic protocol to be administered. A total of 322 cases with patients with CSOM including all age groups and both sexes who attended the outpatient, Dept. of ENT, Govt. Medical College Hospital, TVM during the period of March 2013 to February 2014 (1 year) were studied. Majority of CSOM cases were due to bacteria (73%) and fungi accounted for 22% of the total culture positive cases. Among the bacterial isolates 92.8% were monomicrobial and 7.2% were polymicrobial. Combined bacterial and fungal infections was 9%. Among the bacterial isolates, gram negative organisms (65.3%) account for the majority and gram positive bacteria accounted for 34.7%. The most common bacterial isolate was pseudomonas aeruginosa (56%) followed by staphylococcus aureus (34.7%), Klebsiella pneumonia (3.8%), Escherichia coli (3%), proteus mirabilis (1.7%), proteus vulgaris (0.4%), and Acinetobacterbaumanii (0.4%). The most common fungi isolated was Aspergillus species (82%) followed by Candida (13.8%) and pencillium species (42%).

Keywords: CSOM, pseudomonas aeruginosa, staphylococcus aureus, MRSA, Aspergillus niger.

References

  1. Ballal M, Jyothirlatha, Kishor J et. al. Chronic suppurative otitis media – A bacteriological and mycological study. Indian journal of otolaryngology and Head and Neck 1992 : 1 (1) 10 – 13
  2. Brook Itzhak. Microbiology of otitis media. Indian journal of Otolaryngology 1996 : 2 (1) : 26 – 29
  3. Gulathi, Sudesh Kumar. Investigative profile in patients of chronic suppurative otitis media. Indian journa of Otology 1997; 3 (2) 59 – 62
  4. Kenna MA Treatment of chronic suppurative otitis media. OtolaryngolClin. North Am, 1994, 27 (3). 457 – 472.
  5. Maqbool M. Text book of Ear, Nose and Throat Disease. 8th edition, New Delhi, Jaypee Brothers, 2008
  6. Nikakhlaghs, Khosravi AD, Fazlipour A. et al. Microbiological findings in patients with chronic suppurative otitis media J. Medical Science 2008, 8 : 503 – 506.
  7. Text Book of Medical Mycology, 3rd Edition, 2012, 266-290.
  8. Nandy A, Mully PS, Sivarajan K, Chronic suppuratie otitis media – A bacteriological study. Indian Journal of Otolaryngology 1991, 43 (3), 136-138.
  9. Mohan Urmil, Jindal Neeraja, Fungal and bacterial flora of chronic suppurative otitis media in Amritsar. IJO and HNS 198, 50 (2) 175-177.
  10. Mansoor, Musani, G Khalid et al. Pseudomonas aeruginosa in CSOM. Sensitivity spectrum against various antibiotics in Karachi. J. Ayub Med. Coll. Abottabad 2009; 21 (2) : 120 – 123
  11. Kumar S, Sharma R, SaxenaAk et al study of bacterial flora and sensitivity to antibiotics in cases and CSOM. Indian J otol 2008 : 14 : 20 – 24
  12. Kwon – Chung KJ and Bennet. Medical Mycology 1992.
  13. Vijaya D, Nagaratnamma. T. Microbiological study of Chronic suppurative otitis media. Indi. J. of Otol 1998; 4 (4) 172-174
  14. Gupta V, Gupta A and Sivarajan K. Chronic suppurative otitis media, an aerobic microbiological study. Indian Journal of otology. 1998 June, 4 (2) : 70 – 82
  15. MosafariNia K, Sepheri G, Khatmihetal Isolation and antimicrobial susceptibility of bacteria from CSOM patients in Kerman, Iran. IRCMJ 2011, 13 (12) : 891 – 894
  16. Purnajaf A, Ardebili A, Goudarzi L etal, PCR based identification of MSRA strains and their antibiotic resistant profiles. Asian Pac J Trop Biomed 2014, 4 (SI) : S 293 – 297.

Corresponding Author

Dr Lancy.J

Additional Professor,

Govt. Medical College, Trivandrum