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Category: Volume 05 Issue 10 October 2017
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Title: Urinary Iodide Excretion Studies in Thyroid Patients in North Kerala

Authors: Minikumari Amma.V., Anu.E.B., P.S.Harikumar, Indu Sasidharan

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i10.175

Abstract

Background: Iodine is a micronutrient for the synthesis of thyroid hormones. The decreased production of thyroid hormone results in hypothyroidism. One of the reasons for hypothyroidism is iodine deficiency. The prevalence of thyroid disease is very high in Kerala even after implementing universal salt iodization. The aim of this study was to find out whether the iodine intake is normal in thyroid patients consuming only non-iodized salt.

Methods: The study was conducted among the thyroid patients attending the Out Patient Departments of Kozhikode Medical College. Through thyroid hormonal assay, well established cases of hypo and hyper thyroid patients were taken under study. 24hr urine samples from 500 thyroid patients and 500 normal controls were collected. 24 hr urinary iodide estimation was done in the CWAL of CWRDM, Kunnamangalam.

Result: The average urinary iodide excretion was found to be 190, 188.2,187.9 and 190 µg/day in hypo, their control, hyper and their control respectively.

Conclusion: Nutritional iodine deficiency is not the major problem as judged by urinary iodide excretion study.

Keywords: Iodine deficiency, urinary iodide, hypothyroidism

References

  1. Matovinovie J, Ramalingaswami V Therapy and Prophylaxis in endemic goitre.1960
  2. Hye Rim Chung, Ann. Paediatric Endocrinal metabolism. 2014 ;March 19(1)
  3. Rogina B, Dubravcic M, Microdetermination of iodides by arresting the catalytic reduction of ceric ions. Analyst. 1953; 78:38
  4. C.Carrison, R., Observations on endemic cretinism in the chittal and Gilgit valleysLancet.1908;2:1275.
  5. Ramalingaswamy V, Subramanian T A .The etiology of Himalayan Goitre. Lancet.1961; 1:791
  6. Ramalingaswamy V, Endemic goitre in South East Asia. Ann. Int. Med. 1973;78;277
  7. S.C, Isichei.U.P. West Afr. J. Medicine.  1998; April-June 17(2): 113-120.
  8. P. J. Medi. Asso. Thailand. 1999; March 82(3): 284-9.
  9. S, Pedersen.K.M. Eur. J. Endocrinol.  2001; 144(5) : 461-5.
  10. C.D,Colls.A.J. Br. J. Nutrition. 1997; Dec 78(6): 901-12.
  11. Tapaskumar Sen. (Dissertation Project). Assessment of iodine deficiency disorders in North 24 Parganas District, West Bengal, India.
  12. R.K,Tandon.N, Gupta.N, Karak. A.K, Verma.K,KochuPillai.N. Residual goitre in the post iodization phase. Iodine status, thiocyanate exposure and Autoimmunity. Clin. Endocrinol. 2003; 59: 672-81.
  13. U. M,Padak.P. Assessment of iodine deficiency in Ernakulam District, Kerala state.  Indian Paediatrics. 1999; 36: 178-80.
  14. A.K,Singh .L.H, Tripathy.S, Dehra. A, Khanam. J. Iodine Nutritional status of children in North East India. Indian .J.of Paediatrics.2006; 73: 795-8
  15. Nishad Kerakada, Ganesh Manikantan, Meer.M. Chisthi. International Surgery Journal. 2017;Feb 4(2):680-684.

Corresponding Author

Dr Minikumari Amma.V.

Department of Biochemistry, Government Medical College, Thiruvananthapuram

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Phone: 9496910448