Title: A Study on Role of Alcohol and LFT in Liver Abscess

Authors: Dr Nivash.S, Dr Kabalimurthy.J, Dr Stalin Raja.C

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i10.127

Abstract

Liver abscess is a common surgical problem in our country. This study was carried out to determine the clinicopathology, role of alcohol and LFT in liver abscess, including the various modalities of treatment and its efficacy. Fifty patients from Surgery department of Rajah Muthiah Medical College and Hospital during the period of October 2015 to October 2017 were selected. On analysing the risk factors, as expected, chronic alcoholism was the predominant risk factor, seen in 16 patients (32%), with diabetes seen in five patients and systemic hypertension seen in four patients. Both Diabetes Mellitus and systemic hypertension was seen in seven patients (14%). Thirty six percent of the patients had no identifiable risk factor. Thus this study showed Chronic Alcohol intake is a definitive risk factor for development of liver abscess. Though alcoholism is a predisposing, it has no role in the etiology and liver function test didn’t show much alteration.

Keywords: Liver Abscess, Pigtail catheter, Laparotomy, Alcoholic.

References

  1. Krige JE, Beckingham IJ: ABC of diseases of liver, pancreas, and biliary system. BMJ 2001, 322(7285): 537-540.
  2. Huang CJ, Pitt HA, Lipsett PA, Osterman FA Jr, Lillemoe KD, Cameron JL, Zuidema GD: Pyogenic hepatic abscess. Changing trends over 42 years. Ann Surg 1996, 223(5): 600-607, Discussion 607-609.
  3. Ochsner A, DeBakey M, Murray S: Pyogenic Abscess of the Liver II. An Analysis of Forty-Seven Cases with Review of the Literature. Am J Surg 1938, XL:292-319.
  4. Branum GD, Tyson GS, Branum MA, Meyers WC: Hepatic abscess. Changes in etiology, diagnosis, and management. Ann Surg 1990, 212(6): 655-662.
  5. Rahimian J, Wilson T, Oram V, Holzman RS: Pyogenic liver abscess: recent trends in etiology and mortality. Clin Infect Dis 2004, 39(11):1654-1659.
  6. Farges O, Leese T, Bismuth H: Pyogenic liver abscess: an improvement in prognosis. Br J Surg 1988, 75(9):862-865.
  7. Kini PM, Mammi MKI. Hepatic Amoebiasis in Kerala. J Ind Med Assoc. 1970;55:7-9.
  8. Chen SC, Huang CC, Tsai SJ, Yen CH, Lin DB, Wang PH, Chen CC, Lee MC: Severity of disease as main predictor for mortality in patients with pyogenic liver abscess. Am J Surg 2009, 198(2):164-172.
  9. Ravinder PS. Makkar, Gopal Kr. Sachdev, Veena malhotra. Alcohol consumption, hepatic iron load and the risk of amoebic liver abscess; a case control study. Intern Med. 2003;42:644-9.
  10. Malik AA, Bari SU, Rouf KA, Wani KA: Pyogenic liver abscess: Changing patterns in approach. World J Gastrointest Surg 2010, 2(12):395-401.
  11. Bari S, Sheikh KA, Ashraf M, Hussain Z, Hamid A, Mufti GN: Ascaris liver abscess in children. J Gastroenterol 2007, 42(3):236-240.
  12. Chung YF,  Tan  YM,  Lui  HF,  Tay  KH,  Lo  RH,  Kurup  A,  Tan  BH: Management of pyogenic liver abscesses - percutaneous or open drainage? Singapore Med J 2007, 48(12):1158-1165, quiz 1165.
  13. Hope WW, Vrochides DV, Newcomb WL, Mayo-Smith WW, Iannitti DA: Optimal treatment of hepatic abscess. Am Surg 2008, 74(2):178-182.
  14. Rintoul R, O’Riordain MG, Laurenson IF, Crosbie JL, Allan PL, Garden OJ: Changing management of pyogenic liver abscess. Br J Surg 1996, 83(9): 1215-1218.
  15. Nazir NT, Penfield JD, Hajjar V: Pyogenic liver abscess. Cleve Clin J Med 2010, 77(7):426-427.
  16. Hui JY, Yang MK, Cho DH, Li A, Loke TK, Chan JC, Woo PC: Pyogenic liver abscesses caused by Klebsiella pneumoniae: US appearance and aspiration findings. Radiology 2007, 242(3):769-776.
  17. Rajak CL, Gupta S, Jain S, Chawla Y, Gulati M, Suri S: Percutaneous treatment of liver abscesses: needle aspiration versus catheter drainage. AJR Am J Roentgenol 1998, 170(4):1035-1039.
  18. Porras-Ramirez G, Hernandez-Herrera MH, Porras-Hernandez JD: Amebic hepatic abscess in children. J Pediatr Surg 1995, 30(5):662-664.

Corresponding Author

Dr Nivash.S

Post Graduate, Department of General Surgery,

Rajah Muthiah Medical College and Hospital,

Annamalai University, Annamalai Nagar – 608002