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Category: Volume 05 Issue 09 September 2017
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Title: Role of Argyrophilic Nucleolar Organiser Region Staining in Effusions for Detection of Malignancy - Diagnostic Test Evaluation

Authors: Dr Maria Rose Palathingal, Dr Freena Rose, Dr P.H Prasad

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i9.71

Abstract

The frequency of AgNORs within the nuclei is higher in malignant cells than in normal, reactive or benign neoplastic cells. 80 serous effusions received in the Cytology Lab during the study period, which could be proved as benign or malignant by biopsy were included & AgNOR study  was done.  Statistically significant difference was noted in AgNOR size, count, dispersion & mean AgNOR value between benign & malignant effusions. AgNOR study appears to be clinically useful as an additional diagnostic tool in serous effusion when the cytologic diagnosis is difficult.

Keywords: AgNOR Staining,benign and malignant effusions.

 

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Corresponding Author

Dr Freena Rose

Assistant Professor, Dept of Pathology, Government Medical College, Thrissur, Kerala, Pin 680596

Phone No: 9446551832, 0487 2204832, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.