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Category: Volume 05 Issue 09 September 2017
Hits: 1964

Title: Clinicopathological Study of Ectopic Pregnancy

Authors: Medha Pradeep Kulkarni, Kalpana Ranjitsingh Sulhyan, Akshata Jaywant Parab

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i9.62

Abstract

Pregnancy is a God given boon to any woman but when it gets complicated by means of an ectopic it can be a bane to the conceiving mother with its varied complications to the mother as well as the developing fetus. Ectopic pregnancy (EP) is a major cause of maternal mortality during the first trimester of pregnancy accounting for 10-15% of all maternal deaths globally[1]. Early diagnosis of ectopic pregnancy reduces the risk of tubal rupture and allows for conservative medical management [2].The histopathological examination of the ectopic pregnancy specimen serves two purposes, first it confirms the diagnosis of EP and second it aids in the diagnosis of other findings predisposing to EP like chronic salpingitis and salpingitis isthmica nodosa. Hence the present study was undertaken to study the histopathological findings of EP, correlate these with clinical features and determine the prevalence of pelvic inflammatory disease (PID) in our patients.

The study included 55 cases of EP. Clinical and radiological findings were correlated with the microscopic features in every case.

The study period was 2.5 years from January 2015 to June 2017. 54 out of 55 cases were tubal EP while one was ovarian EP. Common site in the tube was ampulla (49 cases,89.1%).31(57.4%) cases presented with rupture. Chronic salpingitis including follicular salpingits accounted for 36 cases(62.70%).

Keywords: ectopic pregnancy, tubal, pelvic inflammatory disease.

 

References

  1. Mahboob U, Mazhar SB. Management of ectopic pregnancy: a two year study.J Ayub Med Coll Abottabad. 2006;18:34-7
  2. Barnhart KT. Ectopic pregnancy. N Engl J Medicine. 2009;361:379-87.
  3. Ectopic Pregnancy.In William’s Obste-trics. Cunningham GF,Leveno KJ, Bloom SL, Spong CY,Hoffman BL, Dashe JS, Casey BM,Sheffield JS (eds). 24th edition 2014McGraw-Hill, USA pp377-386.
  4. Zheng W, Robboy SJ. Fallopian Tube.In Robboy’s Pathology of the Female Reproductive Tract.Robboy SJ,Muttler GL,Prat J,Bentley RC, Russel P,Anderson MC(eds).2nd Edition 2009,Churchill Livingstone.Elsevier,China.pp487-498.
  5. Sindhura M, Sailatha R, Famida AM, Vijayalakshmi K, Sathiya S, Renuka S. Trends in ectopic pregnancy: a retrospective clinical study of 79 cases. Int J Reprod Contracept Obstet Gynecol 2017;6:3009-13.
  6. Mufti S, Rather S, Mufti S,  Rangrez RA, Wasiqa, Ectopic pregnancy :An anaylsis of 114 cases.JK-Practitioner 2012;17:20-23.
  7. Gorva A, Karre S, Veergandham S Histopathological Study of Ectopic Pregnancies – A Rare case of Bilateral Ectopic Pregnancy IOSR-JDMS 2015;14:42-45
  8. Yadav DP, Bhati I, Bhati BS.Ectopic pregnancy: a comprehensive analysis of risk factors and management. Int J Reprod Contracept Obstet Gynecol 2016;5:2723-7.
  9. Chate MT, Chate B, Chate. Clinical study of ectopic pregnancy. Int J Reprod Contracept Obstet Gynecol 2017;6:3498-3501.
  10. Panti A, Ikechukwu NE, Lukman OO, Yakubu A, Egondu SC, Tanko BA. Ectopic pregnancy at Usmanu Danfodiyo University teaching hospitalSokoto: a ten year review. Annals of Nigerian Medicine.2012;6:87-91
  11. Majhi AK,Roy N,Karmarkar RS,Banerjee PK. Ectopic pregnancy -5 year experience. J Obstet Gynecol Ind.2002;52:55-8.
  12. Bouyer J , Coste J, Fernandez H, Pouly JL, Spira NJ. Sites of ectopic pregnancy : a 10 year population based study of 1800 cases.Human Reproduction 2002; 17: 3224-3230.
  13. Das S,Kalyani V,Lakshmi V, Harendra kumar ML.Ovarian pregnancy. IJPM 2008;51: 37-38.
  14. William PC,Malvar TC,Icneft JR. Term ovarian pregnancy with delivery of live female infant.Am J Obstet Gynecol; 1978;10:132-4.
  15. Sharma R,Biligi D.A study of histopathological changes in fallopian tubes in ectopic pregnancy.Int J Cur Rev 2015;7:54-8.
  16. Peterson HB,Xia Z,Hughes JM,Wilcox LS,Taylor LR,B.S, Trussel J.The risk of ectopic pregnancy after tubal sterilization. N Eng J Med 1997;336:762-767.
  17. Hankins GD,Clark SL,Cunningham FG.Gilstrap LC.Ectopic pregnancy. In: operative obstetrics. Norwalk, Conn: Appleton &Lange,1995:437-56
  18. Clausen I.Conservative versus radical surgery for tubal pregnancy. A review.Acta Obstet Gynecol Scand. 1996;75:8-12.
  19. Edelman DA,Porter CW The intrauterine device and ectopic pregnancy: Contracep-tion Jul;36:85-96
  20. O’Neill SM,Khashan AS,KennyLC, Geene RA, Henriksen TB, Lutomski JE,  Kearney PM. Cesarean section and subsequent ectopic pregnancy: a   systematic review and meta-analysis. BJOG Int J Obstet Gynecol2013;120:671-680.

Corresponding Author

Akshata Jaywant Parab

Department of Pathology, Government Medical College and Hospital, Miraj Maharashtra, India

Contact no: 9975178751, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.