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Category: Volume 05 Issue 09 September 2017
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Title: Analysis of Specific Proteins for the Detection of Early Pregnancy in Cattle, A Review

Authors: Er. S. Shekhar Mohapatra, Ms. Anshurekha Dash, Dr Manoj Kumar Jena

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i9.61

Abstract

Cattle play important role in economy of India as it is the largest milk producer in world. Different dietary products can be derived from Cattles which are rich in different nutrients. Not only for food but Cattles are also used for ploughing. Keeping all these insight the numbers (quantity) as well as quality of cattle is also needed to be improved. More numbers of Cattles can be found among live stocks where the fertility of live stocks is good. Different factors affect the fertility of them. Their nutrition, environment, disease resistance power, different proteins and enzymes and hormones. Protein, enzymes and hormones are plays the key role in efficiency of pregnancy in cattle. The estrous cycle of cattle also plays a very important role in highly fertile cattle. Cows having a perfect estrous cycle can give birth more qualitative off springs. Difference in different proteins can also be found in pregnant cows and non pregnant cows. During estrous cycle and also during gestation period fluctuations of different proteins takes place at high levels. The proteins are expressed by different genes which get activated during the pregnancy period. During different stages of gestation period also difference in protein levels are found by experiments. But now a day due to several dysfunctioning early pregnancy diagnoses is needed to avoid the unwanted miscarriage or loss of pregnancy. Due to unusual repeated crossings the loss of pregnancy and abnormality in offspring are found. After fertilization and implantation of embryo chances the loss of pregnancy becomes less and productivity will be increased. The early pregnancy detection can be done by examining different proteins dubbed as pregnancy specific proteins like PAGs, PSPB, uteroglobins, interferon-induced GTP binding proteins etc. Comparison must be done between different proteins, from histotroph and endometrium at estrous stage, pregnant cow and non pregnant cow. After this precaution should be taken to avoid the loss of pregnancy and fertility can be obtained which will come under live stocks management.

Index Terms— IFNT, PAGs, PDBU, PSPB, Progesterone, Uteroglobin, Interferon Induced GTP Binding Proteins.

References

  1. A. Zaied, C. J. Bierschwal, R. G. Elmore, R. S. Youngquist, A. J. Sharp, and H. A. Garverick, “Concentrations of progesterone in milk as a monitor of early pregnancy diagnosis in dairy cows,” Theriogenology, vol. 12, no. 1, pp. 3–11, 1979.
  2. Simersky, J. Swaczynova, D. A. Morris, M. Franek, and M. Strnad, “Development of an ELISA-based kit for the on-farm determination of progesterone in milk,” Veterinarni Medicina, vol. 52, no. 1, pp. 19–28, 2007.
  3. Kamboj and B. S. Prakash, “Relationship of progesterone in plasma and whole milk of buffaloes during cyclicity and early pregnancy,” Tropical Animal Health and Production, vol. 25, no. 3, pp. 185–192, 1993.
  4. K. Batra, R. C. Arora, N. K. Bachlaus, and R. S. Pandey, “Blood and milk progesterone in pregnant and nonpregnant buffalo,” Journal of Dairy Science, vol. 62, no. 9, pp. 1390–1393, 1979.
  5. M. Perera, N. Pathiraja, S. A. Abeywardena, M. X. Motha, and H. Abeygunawardena, “Early pregnancy diagnosis in buffaloes from plasma progesterone concentration,” Veterinary Record, vol. 106, no. 5, pp. 104–106, 1980.
  6. Singh and R. Puthiyandy, “Estimation of progesterone in buffalo milk and its application to pregnancy diagnosis”  Jour-nal of Reproduction and Fertility, vol. 59, no. 1, pp. 89–93, 1980.
  7. Isobe, M. Akita, T. Nakao, H. Yamashiro, and H. Kubota, “Pregnancy diagnosis based on the fecal progesterone concentration in beef and dairy heifers and beef cows,” Animal Reproduction Science, vol. 90, no. 3-4, pp. 211–218, 2005.
  8. “Committee on Reproductive Nomencla-ture Recommendations for standardizing bovine reproductive terms,” The Cornell Veterinarian, vol. 62, no. 2, pp. 216–237, 1972.
  9. Ayalon, “A review of embryonic mortality in cattle,” Journal of Reproduction and Fertility, vol. 54, no. 2, pp. 483–493, 1978.
  10. Morris and M. Diskin, “Effect of progesterone on embryo survival, ”  Animal, vol. 2, no. 8, pp. 1112–1119, 2008.
  11. S. E. Hafez, Reproduction in Farm Animalsedition, Lea and Febiger, Philadelphia, Pa, USA, 6th edition, 1993.
  12. A. Cowie, Pregnancy Diagnosis Tests: A Review, Commonwealth Agricultural Bureaux Joint Publication no. 13, Commonwealth Agricultural Bureaux, Oxford, UK, 1948.
  13. Wisnicky and L. E. Cassida, “A manual method for diagnosis of pregnancy in cattle,” Journal of the American Veterinary Medical Association, vol. 113, p. 451, 1948.
  14. Zemjanis, Diagnostic and Therapeutic Techniques in Animal Reproduction, Williams and Wilkins, Baltimore, Md, USA, 2nd edition, 1970.
  15. H. Arthur, D. E. Noakes, H. Pearson, and T. J. Parkinson, “Reproduction in the buffalo,” in Veterinary Reproduction and Obstetrics, WB Saunders, London, UK, 1966.
  16. J. Franco, M. Drost, M.-J. Thatcher, V. M. Shille, and W. W. Thatcher, “Fetal survival in the cow after pregnancy diagnosis by palpation per rectum,” Theriogenology, vol. 27, no. 4, pp. 631–644, 1987.
  17. K. Sharma, J. K. Singh, S. K. Phulia, S. Khanna, and I. Singh, “Fetal sex determination with ultrasonography in buffaloes,” Indian Veterinary Journal, vol. 88, no. 10, pp. 105–107, 2011.
  18. Curran, R. A. Pierson, and O. J. Ginther, “Ultrasonographic appearance of the bovine conceptus from days 20 through 60,” Journal of the American Veterinary Medical Association, vol. 189, no. 10, pp. 1295–1302, 1986.
  19. M. Fricke, “Scanning the future—ultrasonography as a reproductive management tool for dairy cattle,” Journal of Dairy Science, vol. 85, no. 8, pp. 1918–1926, 2002.
  20. G. Paisley, W. D. Mickelsen, and O. L. Frost, “A survey of the incidence of prenatal mortality in cattle following pregnancy diagnosis by rectal palpation,” Theriogenology, vol. 9, no. 6, pp. 481–491, 1978.
  21. Vaillancourt, C. J. Bierschwal, D. Ogwu et al., “Correlation between pregnancy diagnosis by membrane slip and embryonic mortality,” Journal of the American Veterinary Medical Association, vol. 175, no. 5, pp. 466–468, 1979.
  22. Ali and S. Fahmy, “Ultrasonographic fetometry and determination of fetal sex in buffaloes (Bubalus bubalis),” Animal Reproduction Science, vol. 106, no. 1-2, pp. 90–99, 2008.
  23. Han, H. R. Kim, K. Naruse et al., “Identification of bovine pregnancy-specific milk proteins using proteomics,” Biology of Reproduction, vol. 78, p. 143, 2008.
  24. I. Jin, H. R. Lee, H. R. Kim, H. J. Lee, J. T. Yoon, and C. S. Park, “Proteomics analysis of pregnancy-specific serum prot-eins in bovine,” Reproduction, Fertility and Development, vol. 18, no. 1-2, p. 183, 2005.
  25. Karen, S. Darwish, A. Ramoun et al., “Accuracy of ultrasonography and pregnancy-associated glycoprotein test for pregnancy diagnosis in buffaloes,” The-riogenology, vol. 68, no. 8, pp. 1150–1155, 2007.
  26. Ayad, N. M. Sousa, J. Sulon, J. L. Hornick, M. Iguer-Ouada, and J. F. Beckers, “Correlation of five radioimmun-oassay systems for measurement of bovine plasma pregnancy-associated glycoprotein concentrations at early pregnancy period,” Research in Veterinary Science, vol. 86, no. 3, pp. 377–382, 2009.
  27. Silva, R. A. Sterry, D. Kolb et al., “Accuracy of a pregnancy-associated glycoprotein ELISA to determine pregnancy status of lactating dairy cows twenty-seven days after timed artificial insemination,” Journal of Dairy Science, vol. 90, no. 10, pp. 4612–4622, 2007.
  28. A. Green, T. E. Parks, M. P. Avalle et al., “The establishment of an ELISA for the detection of pregnancy-associated glycoproteins (PAGs) in the serum of pregnant cows and heifers,” The-riogenology, vol. 63, no. 5, pp. 1481–1503, 2005.
  29. G. Sasser, C. A. Ruder, K. A. Ivani, J. E. Butler, and W. C. Hamilton, “Detection of pregnancy by radioimmunoassay of a novel pregnancy-specific protein in serum of cows and a profile of serum concentrations during gestation,” Biology of Reproduction, vol. 35, no. 4, pp. 936–942, 1986.
  30. P. Zoli, L. A. Guilbault, P. Delahaut, W. B. Ortiz, and J.-F. Beckers, “Radioimmunoassay of a bovine pregnancy-associated glycoprotein in serum: its application for pregnancy diagnosis,” Biology of Reproduction, vol. 46, no. 1, pp. 83–92, 1992.
  31. H. Kiracofe, J. M. Wright, R. R. Schalles, C. A. Ruder, S. Parish, and R. G. Sasser, “Pregnancy-specific protein B in serum of postpartum beef cows,” Journal of Animal Science, vol. 71, no. 8, pp. 2199–2205, 1993.
  32. Humblot, S. Camous, J. Martal et al., “Diagnosis of pregnancy by radioimm-unoassay of a pregnancy-specific protein in the plasma of dairy cows,” The-riogenology, vol. 30, no. 2, pp. 257–267, 1988.
  33. P. V. L. Telugu, A. M. Walker, and J. A. Green, “Characterization of the bovine pregnancy-associated glycoprotein gene family—analysis of gene sequences, regulatory regions within the promoter and expression of selected genes,” BMC Genomics, vol. 10, article 185, pp. 1–17, 2009.
  34. Klisch, A. Boos, M. Friedrich et al., “The glycosylation of pregnancy-associated glycoproteins and prolactin-related protein-I in bovine binucleate trophoblast giant cells changes before parturition,” Reproduction, vol. 132, no. 5, pp. 791–798, 2006.
  35. Xie, J. Green, J. B. Bixby et al., “The diversity and evolutionary relationships of the pregnancy-associated glycoproteins, an aspartic proteinase subfamily consisting of many trophoblast-expressed genes,” Pro-ceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 24, pp. 12809–12816, 1997.
  36. A. Green, S. Xie, X. Quan et al., “Pregnancy-associated bovine and ovine glycoproteins exhibit spatially and temporally distinct expression patterns during pregnancy,” Biology of Reproduction, vol. 62, no. 6, pp. 1624–1631, 2000.
  37. Martal, N. Chêne, S. Camous et al., “Recent developments and potentialities for reducing embryo mortality in ruminants: the role of IFN-τ and other cytokines in early pregnancy,” Reprod-uction, Fertility and Development, vol. 9, no. 3, pp. 355–380, 1997.
  38. Constanta, S. Camousa, P. Chavatte-Palmera et al., “Altered secretion of pregnancy-associated glycoproteins during gestation in bovine somatic clones,” The-riogenology, vol. 76, pp. 1006–1021, 2011.
  39. M. Mialon, S. Camous, G. Renand, J. Martal, and F. Ménissier, “Peripheral concentrations of a 60-kDa pregnancy serum protein during gestation and after calving and in relationship to embryonic mortality in cattle,” Reproduction, Nutrition, Development, vol. 33, no. 3, pp. 269–282, 1993.
  40. Xie, B. G. Low, R. J. Nagel, J.-F. Beckers, and R. M. Roberts, “A novel glycoprotein of the aspartic proteinase gene family expressed in bovine placental trophectoderm,” Biology of Reproduction, vol. 51, no. 6, pp. 1145–1153, 1994.
  41. E. Butler, W. C. Hamilton, R. G. Sasser, C. A. Ruder, G. M. Hass, and R. J. Williams, “Detection and partial characterization of two bovine pregnancy-specific proteins,” Biology of Reprodu-ction, vol. 26, no. 5, pp. 925–933, 1982.
  42. W. Bazer, W. W. Thatcher, P. J. Hansen, M. A. Mirando, T. L. Ott, and C. Plante, “Physiological mechanisms of pregnancy recognition in ruminants,” Jour-nal of Reproduction and Fertility. Supplement, vol. 43, pp. 39–47, 1991.
  43. Forde, F. Carter, T. E. Spencer et al., “Conceptus-induced changes in the endometrial transcriptome: how soon does the cow know she is pregnant?” Biology of Reproduction, vol. 85, no. 1, pp. 144–156, 2011.
  44. C. Green, C. S. Okamura, S. E. Poock, and M. C. Lucy, “Measurement of interferon-tau (IFN-τ) stimulated gene expression in blood leukocytes for pregnancy diagnosis within 18-20d after insemination in dairy cattle,” Animal Reproduction Science, vol. 121, no. 1-2, pp. 24–33, 2010.
  45. S. Whisnant, L. A. Pagels, and M. G. Daves, “Case study: effectiveness of a commercial early conception factor test for use in cattle,” Professional Animal Scientist, vol. 17, pp. 51–53, 2001.
  46. C. Cordoba, R. Sartori, and P. M. Fricke, “Assessment of a commercially available early conception factor (ECF) test for determining pregnancy status of dairy cattle,” Journal of Dairy Science, vol. 84, no. 8, pp. 1884–1889, 2001.
  47. Morton, A. C. Cavanagh, S. Athanasas-Platsis, K. A. Quinn, and B. E. Rolfe, “Early pregnancy factor has immunosu-ppressive and growth factor properti-es,” Reproduction, Fertility, and Development, vol. 4, no. 4, pp. 411–422, 1992.
  48. Lobago, M. Bekana, H. Gustafsson et al., “Serum profiles of pregnancy-associated glycoprotein, oestrone sulphate and progesterone during gestation and some factors influencing the profiles in ethiopian borana and crossbred cattle,” Re-production in Domestic Animals, vol. 44, no. 4, pp. 685–692, 2009.
  49. Hirako, T. Takahashi, and I. Domeki, “Peripheral changes in estrone sulfate concentration during the first trimester of gestation in cattle: comparison with unconjugated estrogens and relationship to fetal number,” Theriogenology, vol. 57, no. 7, pp. 1939–1947, 2002.
  50. A. Robertson and G. J. King, “Conjugated and unconjugated oestrogens in fetal and maternal fluids of the cow throughout pregnancy,” Journal of Reproduction and Fertility, vol. 55, no. 2, pp. 463–470, 1979.
  51. H. Wimpy, C. F. Chang, V. L. Estergreen, and J. K. Hillers, “Milk progesterone enzyme immunoassay: modifications and a field trial for pregnancy detection in dairy cows,” Journal of Dairy Science, vol. 69, no. 4, pp. 1115–1121, 1986.

Corresponding Author

Er. S. Shekhar Mohapatra

School of Bioengineering and Biosciences

Lovely Professional University, Phagwara, Punjab India 144411