Title: Acute Kidney Injury in Pregnancy—A Single Centre Retrospective Study

Authors: Dr Neeraja. P, Dr Ramadevi. E, Dr Arjumand Bano, Dr Shalini

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i8.156

Abstract

Background: Acute kidney injury continues to be common in developing countries. Its occurrence during pregnancy is a serious complication, involving the prognosis of both the mother and the child.

Aims and Objectives: To investigate the incidence, clinical characteristics, etiology and outcome of AKI during pregnancy in patients reported to the department of Nephrology.

Materials and Methods: Out of 650 AKI patients, 50 (7.69%) were associated with pregnancy. The results of a detailed medical history, physical examination, routine urine analysis, serum creatinine and renal ultrasonography were noted.

Results: The age of patients ranged from 20 to 50 years with a mean of 33.42 ± 5.63 years. 17 (34%) patients were primigravid and 33 (66%) were multigravid. Of the various causes, septic abortion was the commonest cause accounting for 25 (50%) cases, 20 (80) of which occurred in the first trimester and five (20%) in the second trimester.

Conclusion: PRAKI continues to be of significant occurrence accounting for 7.69 % of AKI in our study.

Key Words: Acute kidney injury, pregnancy, septic abortion, serum creatinine.

 

References

  1. Najar MS, Shah AR, Wani IA, et al. Pregnancy related acute kidney injury: A single center experience from the Kashmir Valley. Indian Journal of Nephrology. 2008;18(4):159-161.
  2. Selcuk NY, Onbul HZ, San A, Odabas AR. Changes in frequency and etiology of acute renal failure in pregnancy (1980-1997) Ren Fail. 1998;20:513–7.
  3. Prakash J, Tripathi K, Malhotra V, Kumar O, Srivastava PK. Acute renal failure in eastern India. Nephrol Dial Transplant.  1995;10:2009–12. 
  4. Kumar KS, Krishna CR and Kuma VS. “Pregnancy related acute renal failure”. Journal of Obstetrics & Gynaecology of India. 2006;56 (4):308–310.
  5. Chugh KS. Etiopathogenesis of acute renal failure in the tropics. Ann Natl Acad Med Sci (India) 1987;23:88–99.
  6. Rani PU, Narayen GA. Changing trends in pregnancy related acute renal failure. J Obstet Gynecol India. 2002;52:36–8.
  7. Kilari SK, Chinta RK, Vishnubhotla SK. Pregnancy related acute renal failure. J Obstet Gynecol India. 2006;56:308–10.
  8. Mohamed Arrayhani, Randa El Youbi, Tarik Sqalli. Pregnancy-Related Acute Kidney Injury: Experience of the Nephrology Unit at the University Hospital of Fez, Morocco. ISRN Nephrology. 2013:1-5
  9. Ansari MR, Laghari MS and Solangi KB, “Acute renal failure in pregnancy: one year observational study at Liaquat University Hospital, Hyderabad,” Journal of the Pakistan MedicalAssociation 2008; 58 (2):61–64.
  10. Arora N, Mahajan K, Jana N, Taraphder A. “Pregnancy related acute renal failure in eastern India,” International Journal of Gynecology and Obstetrics. 2010;111 (3): 213–216.
  11. Randeree IGH, Czarnocki A, Moodley J, Seedat YK and Naiker IP. “Acute renal failure in pregnancy in South Africa,” Renal Failure 1995; 17 (2):147–153.
  12. Weinstein L. “Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension in pregnancy,” American Journal of Obstetrics and Gynecology 1982;142 (2):159–167.
  13. Goplani KR, Shah PR, Geraetal DN. “Pregnancy-related acute renal failure: a single-center experience,” Indian Journal of Nephrology 2008;18 (1):17–21.
  14. Erdemoglu M, Kuyumcuoğlu U, Kale A and Akdeniz N. “Pregnancy-related acute renal failure in the southeast region of Turkey: analysis of 75 cases,” Clinical and Experimental Obstetrics and Gynecology 2010;37 (2):148–149.

Corresponding Author

Dr Neeraja. P

Assistant Professor, Department Of Obstetrics & Gynaecology,

Chalemeda Anand Rao Institute Of Medical Sciences, Karimnagar District, Telangana State, India