Title: Comparison of Carotid Intima-media Thickness between Hypertensive Patients and Control Group- A study from rural tertiary care hospital in central India

Authors: Manoj Kumar, Prabhat Kumar Agrawal, Manish Gupta, Vivek Kumar Verma, Santosh Kumar,  Granth Kumar, Sudhir Kumar Yadav, Rajesh Kumar Gautam

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i8.71

Abstract

Introduction: Noncommunicable diseases taking form of pandemic and among them hypertension being commonest of all. Hypertensive patients are at higher risk of atherosclerosis, which in turn leads to increase incidence of MI and stroke. Intima media thickness (IMT) carotid arteries is known to reflect vascular system atherosclerosis as whole. There are limited numbers of studies assessing these parameters in hypertensive patients in Indian population.

Aim: To assess and compare carotid artery Intima-media thickness (IMT) in hypertensive patients and normotensive subjects using high frequency ultrasound.

Materials and Methods: In a case control study, 83 hypertensive patients and 83 normotensive individuals were included as cases and control respectively. After a thorough history taking and clinical examination both the groups were subjected to IMT assessment using high frequency ultrasonography and statistical analysis was done using SPSS.

Results: IMT in all carotid arteries in the hypertensive group was more than that of the normotensive (P < 0.05). It was found that there was no difference between the duration of hypertension and mean IMT in the hypertensive patients.

Conclusion: The present study found that the mean IMT of all carotid arteries in hypertension was more than that of the normotensives, therefore IMT can be used as early evidence of atherosclerosis and with preventive and promotive interventions the consequences of atherosclerosis can be minimized.

Keywords: Atherosclerosis, carotid intima-media thickness, Hypertension, Ultrasound, Rural.

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Corresponding Author

Dr Prabhat Kumar Agrawal

Associate Professor, Dept of Medicine, UPUMS, Saifai, Etawah (UP) – 206130

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