Title: Obstetric Outcome in Elderly Mothers aged 35 Years and above: Comparative Study

Authors: Neerja Singal, Geetanjali Setia, Kiran Kumar Singal

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i8.58

Abstract

Introduction: Many women increasingly delay pregnancy and childbirth into their later decades of life because of different reasons, such as delay in marriage, educational and professional reasons. Advanced maternal age has been regarded as a risk factor for complications in pregnancy.

Objective: This study is aimed at comparing the obstetric outcomes of pregnancy in women aged 35 years and above.

Methods: Prospective comparative observational study was done over a period of 2 year at the M.M.Medical College & Research Centre, Mullana, Ambala (Haryana) India.

Forty pregnant women of age 35 years and above at any gestational age were taken into the study population irrespective of the parity. Forty control population was pregnant women of age 20-34 years of any parity.

Results: The incidence of pre-gestational diabetes, gestational diabetes and preeclampsia was found to be higher in the study group. 65% patients in the study group had Cesarean section. 25% underwent vaginal delivery. In the control group, 80% delivered vaginally. This study did not find any increased incidence of malpresentation in elderly women.

Conclusion: Pregnancy in older multiparous women seem to have higher rates of obstetric complications and such as hypertension, diabetes. Women should be informed that the risk of pregnancy complications increases with age.

Keywords:  maternal age,gestational diabetes,maternal outcome.

References

  1. Balasch J and Gratacos E, “Delayed childbearing: effects on fertility and the outcome of pregnancy,” Fetal Diagnosis and Therapy, 2011; vol. 29, pp. 263–273.
  2. Bayrampour H, Heaman M, DuncanKA, and Tough S,“Advanced maternal age and risk perception:  a qualitative study,” BMC Pregnancy Childbirth, 2012; vol. 12, article 100.
  3. Bianco A, Stone J, Lynch L, Lapinski R, Berkowitz G,Berkowitz R. Pregnancy outcome at age 40 and Obstet Gynecol 1996;87:917–22.
  4. Berkowitz GS, Skovron ML, Lapinski RH, Berkowitz RL.Delayed childbearing and the outcome of pregnancy.N Engl J Med 1990;322:659–64.
  5. Cnattingius S, Forman M, Berende SH, Isotalo. Delayed childbearing and risk of adverse perinatal JAMA.1992;268:886 –90.
  6. Prysak M, Lorenz R, Kisly A. Pregnancy outcome in nulliparous women 35 years and older. Obstet Gynecol.1995;85:65–70.
  7. Seoud M, Nassar AH, Usta IM, Melhem Z, Kazma A,Khalil AM. Impact of advanced maternal age on Pregnancy out come. Am J Perinatol 2002;19:1–7.
  8. Vercellini P, Zuliani G, Rognoni MT, Trespidi L, Oldani S, Cardinale A. Pregnancy at forty and over: a case control study. Eur J Obstet Gynecol Reprod Biol 1993;48:191–5.
  9. Ales K, Druzin M, Santibi D. Impact of advanced maternal age on the outcome of pregnancy. Surg Gynecol Obstet.1990; 171:209 –16.
  10. Kirz DS, Dorchester W, Freeman RK. Advanced maternal age: the mature grav-ida. Am J Obstet Gynecol 1985;152:7–12.
  11. FranzM B and Husslein PW, “Obstetrical management of the older gravida,” Women’s Health, 2010; vol. 6, no. 3, pp. 463–468.
  12. Tabcharoen C, Pinjaroen S, Suwanrath C, and Krisanapan O,“Pregnancy outcome after age 40 and  risk of low birth weight,” Journal of Obstetrics and Gynaecology, 2009;vol. 29, no. 5, pp.378–383.
  13. Jahromi BN and Hussein Z, “Pregnancy outcome at maternal age 40 and older,” Taiwanese Journal of Obstetrics and Gynecology, 2008;vol. 47, no. 3, pp. 318– 321.
  14. Eisenberg VH and Schenker JG, “Pregnancy in the older woman: scientific and ethical aspects,”  International Journal of Gynecology and Obstetrics, 1997;vol. 56, no. 2, pp. 163–169
  15. Gilbert WM, Nesbitt TS, Danielsen B. Childbearing beyond age 40: pregnancy outcome in 24032 Obstet Gynecol. 1999;93:9-14.
  16. Chan BCP, Lao TT. Influence of parity on the obstetric performance of mothers aged 40 years and Hum Reprod. 1999;14:823-37.
  17. Cleary-Goldman J, Malone FD, Vidaver J, Ball RH, Nyberg DA, Comstock CH, Saade GR, et al. Impact of maternal age on obstetric outcome. Obstet Gynecol 2005; May;105(5 Pt 1):983-90.
  18. Joseph KS, Alexander C. Allen, Linda Dodds, Linda Ann Turner, Heather Scott, Robert Liston. The perinatal effects of delayed childbearing. Obstet Gynecol. 2005;105:1410-8.
  19. Chloe Z, Ruth CF. Pregnancy and advanced maternal age. Progr Obstet Gynecol. 2007;17:113-24.
  20. Sahu T. Meenakshi, Agarwal Anjoo, Das Vinita. Advanced maternal age and obstetric outcome. J Obstet Gynecol India. 2007;57:320-3.
  21. Bobrowski R, Bottoms S. Underappr-eciated risks of the elderly multipara. Am J Obstet Gynecol.1995 ;172:1764–70.
  22. Ziadeh S and Yahaya A, “Pregnancy outcome at age 40 and older,” Archives of Gynecology and Obstetrics 2001; vol. 265, no. 1, pp.30–33.

Corresponding Author

Kiran Kumar Singal

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.