Title: The BODE Index and Health Related Quality of Life-Is there a correlation in COPD?
Authors: Venugopal K.P, Thomas George P, Kiran VN, Jain G
DOI: https://dx.doi.org/10.18535/jmscr/v5i8.44
Abstract
Context: COPD a progressive respiratory disease, leads to permanent disability & a negative impact on the quality of life. BODE index ,a multidimensional index provides prognostic information in COPD patients but it is not known whether it can be used as a sensitive tool for predicting the Health related quality of life(HRQoL). HRQoL is assessed using the St George Respiratory Questionnaire validated for the Indian population.
Aims: To Study correlation between BODE Index and HRQoL among stable COPD Patients.
Settings and Design: Cross sectional study conducted in a tertiary care center with a Pulmonology Outpatient department.
Methods and Material: The study was conducted among 50 stable COPD patients aged above 40 years for 12 months. The BODE index score and HRQoL were measured.
Statistical analysis used: A Spearman’s(ρ) &Pearson’s correlation coefficient (r) analysis were done to find out the correlation between different variables
Results: The BODE index was categorized into quartiles:0-2,3-4,5-6&7-10.Mean total SGRQ scores and scores of individual components of the SGRQ increased with the increase in BODE index quartiles. Strong correlation (ρ =0.922;p < 0.001)were found between baseline mean total SGRQ scores and BODE quartiles. When the individual components of BODE index were assessed, FEV1 % predicted and 6MWD had negative correlations and mMRC dyspnea grades had a positive correlation with the total SGRQ score. A lower BMI (≤21) was associated with higher total SGRQ score and vice versa.
Conclusion: Higher BODE quartiles were associated with higher SGRQ scores (worse health status). BMI and 6MWD showed a significant correlation with health related quality of life.
Key-words: COPD,BODE, SGRQ,HRQoL
Key messages: Lung function and exacerbation frequencies incorporated in GOLD guidelines for therapy decisions and prognostication ignores the Quality of life experienced by a patient. Multidimensional indices like BODE correlate well with health status assessed by the St George Respiratory Questionnaire and should be incorporated in future COPD guidelines.
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