Title: Microbiological Aspects and Conventional Methods for Diagnosis of Neonatal Sepsis

Authors: Sunil Kumar, Rajesh Kumar, Ajay Kumar, Sanjay Kumar, Satyendu Sagar, Rajeev Ranjan Prasad, Chandan Kumar, Alka Sinha, Prabhat Kumar, Shankar Prakash

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i7.193

Abstract

Background: septicaemia is a major cause of morbidity and mortality among neonates. Its early diagnosis can save lives of many neonates.

Objective: neonatal septicaemia is very difficult to diagnose due to non specific signs and symptoms. Early diagnosis of septicaemia is very important for saving lives of neonates. Study design: the study is conducted in the department of Microbiology and the department of Pediatrics at Patna medical college, Patna. 120 neonates with signs and symptoms of septicaemia were included in this study. Diagnosis is done by conventional method of culture technique.  

Result: result shows that among culture positive cases 68% are male, 33% belong to first week of their lives, and 53% are of low birth weight. Among clinically suspected cases 52% are blood culture positive and the most common organism isolated is Klebsiella pneumoniae.

Discussion and Conclusion: male predominance in neonatal septicaemia shows that there is sex linked factor in host susceptibility. Incidence of septicaemia is highest in first week of life, low birth weight is predisposing factor for septicaemia,. Gram negative bacteria Klebsiella is involved in most of the cases of septicaemia.

Keywords: Sepsis, NICU, SIRS, hypoglycemia, hypothermia, PROM, PPROM, unbooked, leukocytosis, leucopoenia, tachypnea, and tachycardia.

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Corresponding Author

Rajesh Kumar

Assistant professor, Dept. of Microbiology,

Nalanda Medical College, Bhutnath road Patna-800026 (Bihar)

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