Title: Efficacy of Bronchial Brushing Cytology and Its Correlation with Biopsy in Lung Tumours At tertiary care Hospital northern western

Authors: Sharda Dawan, Sunita Bika, Manohar Lal Dawan

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i7.43

Abstract

Background: Bronchial brushing (BB) and the more recent trans-bronchial needle aspiration (TBNA) are well established techniques performed using flexible fiberoptic bronchoscope, for sampling trachobronchial lesions suspected of malignancy.

Material & Method: This study was carried out in department of pathology, Sardar Patel Medical College & Associated Group of Hospitals, Bikaner. This study included 50 cases of clinically suspected lung cancer either primary or metastatic.

Results: The accuracy of Bronchial Brush Cytology in the diagnosis of Squamous Cell Carcinoma was 81.57%; in Bronchogenic Adenocarcinoma accuracy was 80%, in Small Cell Anaplastic Carcinoma 83.33% and in Large Cell Carcinoma it was 100%.

Conclusion: Bronchial brushing is a better technique than Post FOB  in diagnosing lung cancer. If both techniques are used simultaneously, the efficacy of this combination in diagnosis of lung cancer proves much superior to either techniques used alone, probably by addition of their advantageous features, and reducing the chances of their failure, thereby helping in early diagnosis of lung cancer.

Keywords: Bronchogenic carcinoma, bronchial brushing , cytology, histopathology.

References

1.      Ng ABP, Horak GC. Factors significant in the diagnostic accuracy of lung cytology in bronchial washing and sputum samples: II. Sputum samples. Acta Cytol 1983; 27 : 397-402.

2.      Reynolds HY. Bronchoalveolar lavage. Am Rev Respir Dis 1987; 135 : 250-63.

3.      Husain AN, Kumar V. The lung. In: Kumar V, Abbas AK, Fausto N, editors. Robbins and Cotran pathologic basis of disease. 7th ed. India: Saunders; 2004. p. 711-72.

4.      Gaur DS, Thapliyal NC, Kishore S, Pathak VP. Efficacy of broncho-Alveolar Lavage and Bronchial Brush Cytology in Diagnosing Lung Cancers. Journal of Cytology 2007; 24 (2): 73-77.

5.      Stringfield JT, Markowitz DJ, Bentz RR, Welch MH, Weg JG. The effect of tumor size and location on diagnosis by fiberoptic bronchoscopy. Chest. 1977 Oct; 72(4):474-6.