Title: Neonatal Septicemia: Bacterial Isolates & Their Antibiotics Susceptibility Patterns: A Hospital Based Study

Authors: Dr Basavaraj M S, Mr Rashmiranjan Rout, Gagan Priya Pandey

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i6.181

Abstract

In neonates, sepsis incidence is increasing in the recent years. Neonatal septicemia is an important cause of morbidity & mortality among neonates in India, with an estimated incidence of approximately 4% in intramural live births. This present study was undertaken to study the bacteriological profile of neonatal septicemia cases and their antibiotic sensitivity pattern for planning strategy for the management of these cases. Neonatal septicemia is a life threatening emergency, and rapid treatment with antibiotics is essential for a favorable outcome. Classical empirical treatment of neonatal sepsis consists of amoxicillin & an aminoglycoside. In present study, S.aureus & Gram-negative isolates were frequently found to be resistant to amoxicillin & an aminoglycoside also, thus indicating that the use of these drugs might be ineffective. Therefore great caution is required in selection of antibiotic therapy.

Keywords:  Neonatal septicemia, Bacterial Isolates & antibiotic susceptibility.

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Corresponding Author

Dr Basavaraj M S

Associate Professor, Department of Microbiology,

Heritage Institute of Medical Sciences, Varanasi