Title: Observational Study on the Outcome of Supervised and Non-Supervised Therapy in Subject with Pulmonary Tuberculosis
Authors: Rajni Kant, Akhilesh Kumar, Rajiv Kumar, Deepmala Sinha, Sumit Kumar Mahato
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.103
Abstract
Background: The success of anti-tuberculosis programme is directly dependent on the adherence to the treatment, patient compliance, and correct combination of anti-tubercular drugs in the optimum doses for right duration. Lack of adherence to drug gives rise to resurgence and resistance which can be prevented if drug are given under direct supervision.
Aims and Objective: Supervised short-course therapy can have a good impact over patients on non supervised therapy who discontinue their treatment and become treatment failure case. In view of the above scenario the present study has been conducted at RIMS, a tertiary care hospital and adjoining PHC to study the likely impact of supervised over non supervised treatment.
Material and Methods: The present study was carried out in outdoor and indoor patients from the department of medicine, Rajendra institute of medical science, Ranchi and adjoining PHC during the period from October 2016 to April 2017
Result and Conclusion: Both supervised and non-supervised therapy are effective but the revised WHO regimen (DOTS regimen) directly observed short course therapy increases the patient’s compliance and adherence to the treatment regimens and increased sputum smear conversion rate at the end of two months thereby concluding that supervised therapy is superior to non supervised therapy when outcomes were compared.
Keywords: supervised and non supervised, antituberculosis drug, DOTS.
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