Title: A Study of Clinical and Epidemiological Profile of Dengue Fever in Tertiary Care Centre in Central India
Authors: Gopal Krishna, T N Dubey, K Deopujari
DOI: https://dx.doi.org/10.18535/jmscr/v5i6.75
Abstract
Objective: Dengue fever is most important arboviral disease in India and other tropical and subtropical countries with increasing prevalence in recent years with significant morbidity and mortality. This study was aimed to asses clinical & haematological features and outcome in central Indian adult population.
Methods: A cross-sectional observational study undertaken among adult patients admitted in a teaching hospital. 105 patients were analysed. All patients who were IgM-ELISA positive irrespective of their card test status were included in study. Clinical features and haematological, biochemical & radiological findings are noted.
Results: Total 105 dengue patients were included 22 ware of DF, 65 in DHF and 18 were DSS group. Male: female ratio was 1.14:1. Most common age group affected was 21-30 Yrs in 42.8 % cases. 60.5% cases were from urban area. 68.5% cases reported in month of September and October. Clinical features noted most common was fever (96.2%), myalgia (57.1%), headache (40%), vomiting(24%), retro-orbital pain (26.6%), abdominal pain(26.6%), patechie (34.2%), rash (41.9%), positive tourniquet test (56.1%). Major bleeding (25.7%), among them most common was gut bleeding. Complications like ARDS, resp. failure, encephalopathy, MODS were noted in DSS cases. Mean Hb% was 11.6 gm%, mean platelets count was 51286 /cumm. Platelets count 4000-1 lakhs in (63.8%) cases. Blood transfusion required in 43.8% cases. Coagulopathy was noted in 72.2% cases of DSS. Mean hospital stay was 7.43 days. No mortality was noted in our study.
Conclusion: Dengue is increased with increasing urbanisation & poor sanitation. Dengue has wide spectrum of clinical and haematological presentation. Significant mortality occurs in DHF and DSS. It is a low mortality illness if prompt diagnosis and proper fluid management instituted in DHF and DSS. Platelet transfusion has a little role in dengue management.
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Gopal Krishna