Title: Assessment of Risk Factors among Pulmonary Tuberculosis Patients

Authors: Dr Aashutosh Asati, Dr Shubhangi Nayak, Dr Manoj Indurkar

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i5.222

Abstract

 INTRODUCTION: Tuberculosis is a chronic pulmonary disease causing high morbidity and mortality. It has multiple risk factors of which includes various host related and socio-demogrphic factors. HIV is considered the most powerful risk factor for the progression of TB infection to disease. The frequency of tuberculosis occurrence in patients of diabetes mellitus is reported to be 3-4 times than that in non-diabetics. Apart from these there are other underlying risk factors which compromise the immune status like  malignanaciesend-stage renal disease, chronic lung disease, malnutrition, and alcoholism. Apart from host related factors, many environmental and social risk factors have been reported to be involved in increased susceptibility of infection and progression of the disease.

OBJECTIVE: To asses various demographic, socioeconomic and clinical risk factors for pulmonary tuberculosis (PTB) patients.

MATERIAL AND METHODS: Total 117 patients of pulmonary tuberculosis were included in our study. Data regarding socio-demographic risk factors and presence of any existing co morbities was collected.

RESULTS: Majority patients, were males (62%), from rural areas (59%), married (75%), in age group between 20-60 years (75%), below poverty line(61%), low educated, and labourers(37%). 7.6% were HIV infected, 10.2% patients had diabetes mellitus, 13.7% patients were using corticosteroids for treatment of other chronic illness, 26.4% patients were malnourished.

CONCLUSION: The present study reveals that various demographic, socioeconomic and clinical risk factors have a potential role in causation of  pulmonary Tuberculosis, and hence prevention and timely management of these risk factors could be helpful  to reduce the burden of disease.

KEY WORDS - Pulmonary Tuberculosis, Risk factors, co morbidities.

References

1.      Tb india 2016 revised national tb control programme annual status report. New delhi: central tb division, directorate general of health and family welfare, nirman bhavan; 2011. Available from: http://www.tbcindia.nic.in/showfile.php?lid=3180.

2.      Decker CF & Lazarus A (2000) Tuberculosis and HIV infection. Postgraduate Medicine 108, 57–68.

3.      Devi SB, Naorem S, Singh TJ, Singh KB, Prasad L & Devi TS (2005) HIV and TB coinfection. Journal of Indian Academy of Clinical Medicine 6, 220–3.

4.      Singh SK; Pulmonary tuberculosis and Diabetes mellitus. In An update on Respiraroty Medicine. Eds. SK Samaria; JC Matah. 1997; 385-9.

5.      Kumar V, Abbas AK, Fausto N, Mitchell RN (2007). Robbins Basic Pathology (8th ed.). Saunders Elsevier. pp. 516–522. ISBN 978-1-4160-2973-1.

6.      Baker M, Das D, Venugopal K, Howden-Chapman P (2008) Tuberculosis associ-ated with household crowding in a developed country. J Epidemiol Community Health 62: 715-21.

7.      Schoeman JH, Westaway MS, Neethling A (1991) Нe relationship between socioeconomic factors and pulmonary tuberculosis. Int J Epidemiol 20: 435-40.

8.      Lienhardt C, Fielding K, Sillah JS, Bah B, Gustafson P, et al. (2005) Investigation of the risk factors for tuberculosis: a case-control study in three countries in West Africa. Int J Epidemiol 34: 914-23.

9.      Bhatia MS, Bhasin SK, and Dubey KK. Psychosocial dysfunction in tuberculosis patients. Indian J Med Sci. 2000;54:171-3.

10.  Ali M, Imam F, Mallik S, Mehra RK, Kumar P, Garg A. Effect of Social Factors on Tuberculosis Patients: A Comprehensive Illness Behaviour Study. Indian Journal of Pharmacy Practice. 2013;6:61-4.

11.  Dubey KK, Bhasin SK, Bhatia MS. (1999) Impact of Tuberculosis on sexual Relationship Amongst Hospitalized patients. The Indian Practitioner, 52, 680.

12.  Gupta S, Shenoy VP, Mukhopadhyay C, Bairy I and  Muralidharan S. Role of risk factors and socio-economic status in pulmonary tuberculosis: a search for the root cause in patients in a tertiary care hospital, South India. 2011;16:74–8.

13.  Hill PC, Sillah DJ, Donkor SA, Out J, Adegbola RA and Christian Lienhardt C.Risk factors for pulmonary tuberculosis: a clinic-based case control study in The Gambia. BMC Public Health 2006;6:156.

14.  Srivatava AB , Priyank Jain P , Jain S. Prevalence Of Diabetes Mellitus In Active Pulmonary Tuberculosis Patients And Clinico-Radiological Presentation Of Tubercular Diabetic Patients. Int J Res Med. 2016;5;79-83.

15.  Raghuraman S, Vasudevan KP,  Govindarajan S, Chinnakali P, and  Panigrahi KC. Prevalence of Diabetes Mellitus among Tuberculosis Patients in Urban Puducherry. N Am J Med Sci. 2014;6:30–4.

16. Dodor E. Evaluation of Nutritional Status of New Tuberculosis Patients at the Effia-Nkwanta Regional Hospital. Ghana Medical Journal. 2008;42:22-8.

Corresponding Author

Dr Aashutosh Asati

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.