Title: Comparative Study of Quality of Life in Patients Living with HIV/Aids in Telangana Region

Authors: K.Varunraj, Syed Umar Farooq, Dr P.Kishore, Dr D. Sudheer Kumar, Dr V. Chandrashekar

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i5.183

Abstract

Acquired immunodeficiency syndrome (AIDS) is a chronic, potentially life-threatening condition caused by the human immunodeficiency virus (HIV). The world health organization (WHO) has defined quality of life as an “individual’s perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns. It is a descriptive, cross-sectional study which involves comparison of Quality of Life (QOL) between ART and Pre-ART groups. Among 246 subjects, 107(43.5%) were from Pre-ART and 139(56.5%) from ART group. Among 6 domains of QOL, Social domain has shown very low mean scores in ART group when compared to Pre-ART.  This could be because of stigma, discrimination and negative perception towards disease. So Patient Counseling plays a major role to improve QOL

Keywords: HIV/AIDS, CD4 count, Quality of Life, Pre Anti Retroviral Treatment (Pre ART), Anti Retroviral Treatment (ART).

References

1.      Workowski KA, Berman S, & Centers for Disease Control and Prevention: Sexually transmitted diseases treatment guidelines, 2010. MMWR Recomm Rep. 2010; 59(12):1-110.

2.      UNAIDS/WHO. Report on the Global AIDS epidemic, Policy document, UNA-IDS, Geneva. Retrieved August 20 2007 http://unaids.org/EN/media/fact+sheets.asp.

3.      Clayson DJ, Wild DJ, Quarterman P, Duprat-Lomon I, Kubin M, Coons SJ. A comparative review of health related quality of life measures for use in HIV/ AIDS clinical trials. Pharmacoeconomics. 2006;24:751-65.

4.      Aranda-Naranjo B. Quality of life in HIV-positive patient. J Assoc Nurses AIDS Care 2004;15:20-7.

5.      Dos Sanctos ECM, Ivan FJ, Fernanda L. Quality of life of people living with AIDS in São Paulo, Brazil. Rev Saúde Pública 2007;41(Supl. 2)

6.      Nirmal B, Divya KR, Dorairaj VS, Venkateswaren K.  Quality of life in HIV/ AIDS patients. A cross sectional study in India. India J Sex Transm Dis. 2008;29:15-17.

7.      Hays RD, Cunningham WE, Sherbourne CD, Wilson IB, Wu AW, et al. Health-related quality of life in patients with human immunodeficiency virus infection in the United States: results from the HIV Cost and Services Utilization Study. Am J Med. 2000; 108: 714-722.

8.      Call SA, Klapow JC, Stewart KE, Westfall AO, Mallinger AP, et al. Health related quality of life and virologic outcomes in an HIV clinic. Qual Life Res. 2000; 9: 977-985.

9.      Brecht JR, Breitbart W, Galietta M, Krivo S Rosenfeld Bet al. Theuse of highly active antiretroviral therapy (HAART) in patients with advanced HIV infection: Impact on medical, palliative care and quality of life outcomes. J Pain Symptom Manage. 2001; 21: 41-51.

10.  Grossman H. The Dramatic Impact of Highly ActiveAntiretroviral treatment. Med Gen Med. 2006; 8: 57.

11.  Palella FJ Jr, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med. 1998; 338: 853-860.

12.  KalichmanSC,Ramanchadran B, Ostrow D Protease inhibitorsand new AIDS combination therapies: implications for psychological services. 1998; Profess psychol 29: 349-356.

13.  Carr A, Cooper DA Adverse effects of antiretroviral therapy. Lancet 356. 2000; 1423-1430.

14.  Jelsma J, Maclean E, Hughes J, Tinise X, Darder M (2005) An investigation into the health-related quality of life of individuals living with HIV who are receiving HAART. AIDS Care 17: 579-588.

15.  Eller LS1 (2001) Quality of life in persons living with HIV. Clin Nurs Res 10: 401-423.

16.  Ana CR, Leonor L, Marina PG, Eduado R (2010) Relationship among psychopathological symptoms, treatment adherence and quality of life in HIV/AIDS infection. Psicol. Reflex Crit 23: 420-429.

17.  P Bunjoungmanee, K C hunloy, A Tangsathapornpong, T Khawcharoenporn and A Apisarnthanarak. Quality of Life Assessment among Patients Living With HIV/AIDS at a Tertiary Car Hospital in Thailand. Southeast Asian Journal of Tropical Medicine Public Health. 2014 July; volume 45(4); 834-842.

18.  Naveet wig et al. The impact of HIV/AIDS on the quality of life: A cross sectional study in north India. Indian Journal of Medical Sciences. 2006 January; 60(1); 3-12.

19.  National population Commission, Nig& ICF Marcon USA National Demographic and Health survey (2008).

20.  Smith Giri, ManirajNeupane et al. Quality of Life among people living with acquired immune deficiency syndrome receiving anti-retroviral therapy: a study from Nepal. HIV/AIDS-Research and Palliative Care. 2013; vol5; 277-282.

21.  Valentine U Odili, Isibhakhomhen B Ikhurionan, Stella F Usifoh, Azuka C Oparah. Determinants of Quality of Life in HIV/AIDS Patients. West African Journal of Pharmacy (2011); 22(1); 42-48.

22.  Olugbemi Oluseyi Motilewa, Uwemedimbuk Smart Ekanem, Adedeji Onayade and Salami S sule. A comparative study of Health Related-Quality of Life Among HIV patients on PRE-HAART and HAART in Uyo South-Aouth Nigeria. Journal of Antiviral Antiretroviral. 2015 April-24; volume 7 (2); 060-068.

23.  K.H. Rajeev, B. Y. Yuvaraj, M.R. NagendraGowda, S.M. Ravikumar. Impact of HIV/AIDS on Quality of Life of People Living with HIV/AIDS in Chitradurga District, Karnataka. Indian Journal of Public Health, April-June 2012; Volume 56(2); 116-121.

24.  Imam MH et al. Health relatedquality of life among the people living with HIV. Bangladesh Med Res Counc Bull. 2011;37: 1-6.

25.  MahalakshmyT, Premarajan K, Hamide A. Quality of life and its determinants in people living with human immunodeficiency virus infection in puducherry. Indian Journal of Community Medicine. 2011; 36: 203-207.

26.  Hopson ML, Families caring for persons with HIV/AIDS. Journal of Human Behaviour in the social Environmnet. 2007;14(1&2);241-258.

27.  B. Nirmal et al. Quality of life in HIV/AIDS patients: A cross-sectional study in south India. Indian Journal of Sexually Transmitted Diseases 2008; Vol.29(1).

28.  Tuck, I, McCain LN, Elswick RK. Spirituality and Psychosocial Factors in Persons Living with HIV.JAdvNurs. 2001;33 (6);776-783.

29.  Tsevat J, Sherman SN, McElwee JA, Mandell KL, Simbartl LA, Sonnenberg FA, Fowler FJ Jr. The will to live among HIV-infected patients. Annals of Internal Medicine. 1999 March;131(3):194-198.

30.  Cotton S, Puchalski CM, Sherman SN, MrusJM,Peterman AH, Feinburg J, Pargament KI, Justice AC,Leonard AC, Tsevat J. Spirituality and religion in patients with HIV/AIDS. J Gen Intern Med. 2006;S5S13.

31.  Fryback PB, Reinert BR. Spirituality and people with potential fatal diagnoses. Nurs Forum 1999; 34:13- 22.

Corresponding Author

Dr V.Chandrashekar M.D

Principal & HOD Department of Medicine

KMC/MGM Hospital, Warangal

Email: This email address is being protected from spambots. You need JavaScript enabled to view it. Phone: 9346950050