Title: Biochemical and Radiological Changes in Non Alcoholic Fatty Liver Diseases Compare with Obesity

Authors: Rachna Lamichaney, Shweta Dwivedi, Reshu Tewari, Vatsala Misra, S.P. Misra, Manisha Dwivedi

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i5.177

Abstract

Background: NAFLD is considered the most common cause of chronic liver disease worldwide. In the general US population, the prevalence of NAFLD is estimated to be approximately 30%, but much higher estimates are reported in selected high-risk populations, such as Hispanics, obese persons, and patients with type 2 diabetes mellitus (T2DM) or with metabolic syndrome. The purpose of this study to correlate the biochemical & radiological changes in non alcoholic fatty liver disease patients compare with obese   patients.

Material & Methods: 41 cases out of which 25 were male and 16 females recruit for this study. In this study biochemical and radiological   parameters were determined.

Statistical Analysis: Comparison of radiological grade of fatty liver and biochemical parameters we used Pearson Chi square test.

Results: All the biochemical parameters were increased. When the radiological grade was compared with the biochemical findings (FBS, TG and SGPT) individually through Pearson’s formula the p value (>0.05) thus found were not statistically significant for any of the biochemical tests.

Conclusion: In this study we concluded that Non-alcoholic fatty liver disease (NAFLD), radiological and biochemical findings give a good correlation and are equally helpful in assessing the severity of NAFLDS.

Keyword: NAFLD, obesity, body mass index, CHD, Diabetes Mellitus.

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Corresponding Author

Dr Shweta Dwivedi

Lecturer (Department of Biochemistry)

M.L.N Medical College, Allahabad

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