Title: Prevalence of Hyperhomocysteinemia among Pre-Eclampsia Patients of A Tertiary Referral Hospital in South India
Authors: Dr Meera Arun, Dr Mallika Gopinath, Dr Sobhakumari.T, Dr C Nirmala
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.209
Abstract
Introduction: Pre-eclampsia is a pregnancy-specific multisystem disorder and is a leading cause of maternal and fetal morbidity and mortality. Several studies have provided evidences that indicate the involvement of hyperhomocysteinemia in the etiology of pre-eclampsia.
Materials and Methods: A cross sectional descriptive study was conducted in 51 pre-eclampsia patients at ≥ 28 weeks of gestation. A fasting blood sample was collected for estimation of serum homocysteine.
Results: Out of 51 pre-eclampsia patients 32 had hyperhomocysteinemia. The prevalence was 62.7%
Conclusion: The present study found high prevalence of hyperhomocysteinemia among pre-eclampsia patients of South India. This study is relevant in our population where nutritional deficiencies are highly prevalent, and present attempt is the forerunner of further extensive studies, that hopefully come up with results that benefit future obstetrics
Keywords: pre-eclampsia, homocysteine, prevalence.
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