Title: Comparison of Fine Needle Aspiration Cytology and Ultrasonography in Solitary Thyroid Nodule
Authors: Sanjay Kothari, Ramesh Kumar Sah, Tapas Ranjan Gupta, Sayandev Dasgupta, Sipra Sen, Ravela Malathi
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.197
Abstract
Background: There is 4-5 % incidence of clinically apparent thyroid nodules in the general population. The majority (90%) of thyroid nodules are benign as malignancy occurs in only 1 in 10 thyroid nodules. The overall incidence of malignancy in solitary thyroid nodule ranges between 10% and 30%. Ultrasound and fine needle aspiration cytology are advocated as first-line examinations for the assessment of thyroid nodules.
Aims and Objective: To study cytological profile of thyroid lesions and correlate the results with Ultrasonography findings and clinical features.
Material and Methods: This prospective study was carried out on 50 patients with thyroid swelling who came to the department of Surgery and thyroid clinic. FNAC and thyroid USG was done in all patients and results were compared on the end of study.
Result: Out of 50 patients, 33 patients (66%) were of benign FNAC (09 colloid cyst, 02 multi-nodular goiter, 12 colloid goiter, and 04 chronic lymphocytic thyroiditis). Swelling in front of neck 50 (100%) was the most common clinical sign observed. About 76% patients were females and 24% were male. The statistically significant association was found only between in diagnosing multinodular swelling in USG in comparison to FNAC. In rest categories there was no significant differences were observed in both USG and FNAC in assessing thyroid swelling.
Conclusion: Study conclude that for proper diagnosis of thyroid lesion, FNAC is the main diagnostic initial modality. Along with Ultrasonography and Clinical examination it helps to come to the proper diagnosis.
Keywords: Thyroid swelling, Thyroid nodule, Fine needle aspiration cytology (FNAC), Thyroid Ultrasonography (USG).
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