Title: Clinico-epidemiological study of Dengue outbreaks- an overview from Kumaon region of Uttarakhand

Authors: Paramjeet Singh, Mehar Bano, Vinita Rawat, Umesh, Arun Joshi

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i4.194

Abstract

Objectives: a) To know about the certain demographic details of dengue cases

                     b) To determine the clinical profile of the cases.

                     c) To assess the hospital stay period and the outcome of these cases

Material & Methods

Study Design: Cross-sectional observational (record based)

Blood samples were collected from the clinically suspected dengue cases were tested for NS1 antigen and IgM MAC ELISA. Necessary investigations like USG, blood were also carried out. Standard WHO definition were used to define dengue, DHF and DSS.

Observations: A total of 239 patients, attending STGH Hospital, Haldwani between August and December 2015 and 97 patients in the 2 months in 2010 were included in the study. Dengue was suspected when two or more of the following symptoms were present: fever, retro-orbital pain, myalgia, arthralgia, skin rash, nausea/vomiting, and hemorrhagic manifestations. Complete blood counts and liver function tests were carried out. In the year 2015 the percentage of DHF-I and DHF-II cases in the study was 7.53% (n=18) and 1.67% (n=4) respectively with a total of 9.2% while the DSS cases were 3.25%(n=8). Whereas the proportion of DHF cases in 2010 was 12.36% higher than in 2015 but no severe DSS was found. As the severity and number of dengue cases with DSS was less in the year 2010 the period of stay in the hospital was comparatively lesser than in 2015.

Conclusions: In the study the pattern of dengue cases in the two outbreaks in different years was seen more in the active age group and males having more outdoor activity were more affected with dengue infection. Certain concomitant conditions like hepatitis, scrub typhus, malaria infection was also observed in dengue cases. Public awareness and public education regarding dengue is of utmost importance for prevention as well as for management of dengue fever.

Keywords: Dengue fever, Thrombocytopenia, Dengue shock syndrome (DSS), Dengue hemorrhagic fever (DHF).

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Corresponding Author

Dr Paramjeet Singh

Associate Professor, Dept of Medicine

Government Medical College, Haldwani, Nainital, Uttarakhand

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