Title: Effect of Disease Activity on Quality of Sleep in Patients of Rheumatoid Arthritis
Authors: Harpreet Singh, Deepak Jain, Arpita Khasnavis
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.145
Abstract
Introduction: In this study we sought to study sleep disturbance in patients of RA and co-relation of quality of sleep with disease activity.
Methods: Fifty patients of RA (as per 1987 ACR criteria) with mild to moderate disease activity as per Clinical Disease Activity Index (CDAI) were included. All these patients were also subjected to Pittsburg Sleep Quality Index (PSQI) Questionnaire for self-assessment of sleep disturbances. Pearson and Spearman’s co-relation coefficients were used for statistical analysis.
Results: The mean age of the subjects for the study was found to be 44.84±11.608 with male: female ratio of approximately 1:7. The mean CDAI was 16.02±5.626 and mean PSQI score was 8.9±4.156. Of the total fifty patients evaluated, 37 patients were found to be poor sleepers (PSQI>5 – 74%) and of the seven components of sleep evaluated using PSQI, the most disturbed component of sleep were Sleep Quality and Day time Dysfunction. The co- relation between disease activity and sleep disturbances was found to be statistically significant (P value 0.05).
Conclusion: The study elicited that sleep is a confounding factor in the assessment of disease activity of RA, which is indicated by a significant positive co- relation between sleep disturbances and disease activity. Hence, patients of RA need to be assessed periodically for quality of sleep for better disease management.
Key Words: Rheumatoid Arthritis,Clinical Disease Activity Index, Pittsburg Sleep Quality Index, Sleep Quality.
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