Title: Dexmeditomodine as Anaesthetic Adjuvant to Relieve Stress Response in Gynecological Laparoscopic Surgeries
Authors: Dr Sherin Sara Roy, Dr Linette J Morris, Dr Baburaj Chakrapani
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.134
Abstract
INTRODUCTION
DEXMEDITOMIDINE is D-enantiomer of 4(5)-1-2-3-dimethyl phenyl imidazole. It is full agonist at alpha 2c and partial at alpha 2a and 2b receptor. DEXMEDITOMIDINE is a highly selective alpha 2 agonist compared to clonidine with property of sedation, hypnosis, analgesia, sympatholytic and anxiolytic properties, making it an ideal anaesthetic adjuvant. Dexmedetomidine can also be used as anti-shivering agent. [1]
Ever since introduction of Dexmedetomidine in clinical practice in 1999, various studies have been conducted to find use of it in various sub-specialties of anaesthesia.
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