Title: Clinical, Etiological and Prognostic Factors of Cerebral Venous Sinus Thrombosis in Kashmir-North India
Authors: Sheikh Nawaz Ahmad, Raouf Parvaiz Asmi, Gulzar Ahmad Bhat, Rayees Tarry, Tanveer Hassan, Mudasir Mushtaq
DOI: https://dx.doi.org/10.18535/jmscr/v5i4.100
Abstract
Background: Cerebral venous sinus thrombosis (CVST) has a variable clinical presentation making early diagnosis difficult. A number of prothrombotic states have been implicated in causation of CVST, but results are mixed.
Aims: The study was aimed to find out the clinical, etiological and prognostic factors of CVST in Kashmir-North India.
Materials and Methods: The study was carried out in a tertiary care hospital where all patients of CVST admitted between 1st August 2014 and 31st July, 2016 were included in the study. The enrolled patients were studied for their demographic profile and a 2-5ml blood sample was collected from the subjects as well. Patients were followed up for minimum period of 6 months and outcome was assessed on the basis of morbidity and mortality.
Results: A total of 36 patients of CVST were included in the study. The mean age of the patients was 35.5years with highest representation (38.89%) among 31-40years age group. Headache was present in 94.4%. 30 patients (83.3%) were alive at the end of follow-up and 6 patients died (16.6%). Among various etiological factors purperium has a maximum representation (33.33%). Out of 32 female patients in the study group, 16 (44.44%) female patients had puerperium and 06 (16.66%) had oral contraceptive as a risk factor. Unconscious with purposive movements was observed in 27.78 % of the subjects. Out of 39 patients who survived, 31 cases (79.4%) had no disability symptoms, 5 patients had mild disability (13%) and 3 patients had moderate disability at six months of follow-up.
Conclusion: Purperium appears to be the main etiological factor and headache as the most common system for CVST in study population.
Keywords: Clinical; etiological; prognostic factors, Cerebral Venous Sinus Thrombosis; Kashmir.
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