Title: Role of “Platelet Rich Plasma” in Treatment of Diabetic Foot Ulcers

Authors: Dr Murtuza Aliasger Calcuttawala, Dr Mahendra Bendre, Dr Natasha Menon

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i4.38

Abstract

Non healing diabetic foot ulcers are a major complication in diabetics, being notoriously difficult to heal. Application of Platelet rich plasma gel (PRP), produces multiple growth factors that speed up healing. 

Aims and Objectives - To evaluate the effectiveness and rate of healing of PRP gel in treatment of diabetic foot ulcers.

Materials and Methods - Thirty patients were enrolled into the study and divided into two groups - Group A (PRP group) received once weekly application of PRP gel and Group B (Control group) received saline dressings.

Observations and Results -The % reduction in ulcer surface area (80.33%) and average rate and duration of healing in PRP group was much higher than control group. The average number of dressings in the PRP group was 4.6 while the same in the control group was 64.5. Complete wound healing was seen in 14 out of 15 patients in PRP group.

Conclusion: PRP is highly effective in treatment of diabetic foot ulcers. PRP stimulates the growth of wound healing thus speeding up the duration of hospital stay. PRP is also a safe product without any allergic reactions/ infections.

Key Words: diabetic, foot, ulcer, Platelet, rich, plasma, healing.

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Corresponding Author

Dr Murtuza Aliasger Calcuttawala

Associate Professor in Dept of General Surgery

Dr. D. Y.Patil Medical College and Hospital, Pimpri, Pune-411018