Toxicity impact of Silk dye waste effluent induced Histopathological changes in the Stomach and Intestine of Swiss albino mice Mus musculus and their mitigation using Moringa oleifera leaf powder

Title: Toxicity impact of Silk dye waste effluent induced Histopathological changes in the Stomach and Intestine of Swiss albino mice Mus musculus and their mitigation using Moringa oleifera leaf powder

Author: Serina Khatun

DOI: https://dx.doi.org/10.18535/jmscr/v5i3.156

Abstract

The results on the effect of oral administration of silk dye waste effluent (2ml/day each animal) on histopathology of the stomach and intestine of swiss albino mice. Revealed sever Histopathological effects in the tissues of both stomach and intestine in Group- II and III but reversible mitigation when using M. oleifera leaves powder at orally fixed dose (300mg/kg/b.w/day) at 30 days and 60 days incubation period. There is marked atrophy of musculature, disintegration of mucosal epithelial cells characterized by cytoplasmic vacuolization, nuclear pycnosis and nuclear fragmentation. A significant damage in Brunner’s gland and crypts of liberkuhn but used of Moringa leafs powder it was significantly recovered the damage tissues has been observed.

Keywords: Silk dye waste effluent, Moringa oleifera leaf powder, histopathology of stomach and intestine, Swiss albino male mice.

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Corresponding Author

Serina Khatun

University Department of Zoology, T. M. Bhagalpur University, Bhagalpur

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