Title: Hypomagnesaemia in Diabetes
Authors: Bilal Mohammed, Feroz P Jenner, Harris P, Jesha MM
DOI: https://dx.doi.org/10.18535/jmscr/v5i2.154
Abstract
Background: Relationship between Diabetes Mellitus and minerals has been reported frequently. Recent studies have demonstrated reduced levels of serum magnesium in diabetes mellitus especially in poorly controlled patients. Clinically, there are significant data linking hypomagnesemia to various diabetic micro- and macrovascular complications. Therefore, Mg supplementation may provide a new therapeutic approach to reducing vascular disease in patients with diabetes.
Objective: To study the levels of serum magnesium in diabetic patients in a tertiary hospital in North Kerala.
Methodology: A hospital based cross sectional study was done in all diabetic patients attending the out-patient and in-patient facilities of Department of Internal Medicine at a tertiary hospital in North Kerala between January1st and March 31st 2014. Results: In the study hypomagnesemia was seen in 15.7% of the participants. No significant difference was found in Serum Magnesium neither between genders (p 0.35) nor age (p 0.057). Serum magnesium levels was not seen to have any significant association with duration of diabetes or type of treatment. Significant relation could not be established with other complications associated with type 2 Diabetes Mellitus like hypertension and dyslipidemia. A significant negative correlation was seen between serum magnesium and Fasting blood sugar (p<0.001) as well as HbA1c values (p<0.001). In the present study it was observed that there was significant difference in the level of serum magnesium among controlled and uncontrolled diabetics (p 0.002).
Conclusion: Hypomagnesemia is common in diabetes and negatively correlated with fasting blood sugar but not related to duration or type of treatment taken.
Keywords: Hypomagnesaemia, Diabetes Mellitus.
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