Title: A study of Clinico-Haematological Profile of Acute Dengue Fever

Authors: Neha Shah, Naimish Patel

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i2.146

Abstract

Dengue fever is caused by Flavivirus is a common ailment occurring in the community. The transmission by means of mosquito bites makes it all the more threatening to society. Aim of the study was to establish clinical and haematological correlation of dengue viral infection. A study of 107 indoor sero-positive dengue fever cases was done prospectively. Clinical features and haematological reports were noted and analyzed statistically. Hospitalisation duration data were noted and analysed. Total 503 clinically suspected patients were tested at tertiary care level hospital; out of which 107(21.2%) patients were positive for acute dengue fever. Female: Male ratio, and adult:old ratio was 1.14;1 and 4.5:1, respectively. The maximum 71% cases of acute dengue fever were recorded between the months of September 2016 to December 2016. Clinically fever is commonest symptoms presentation in 97.2% patients, followed by muscle pain and vomiting in 87.3 %, respectively.  Least common clinical presentation was skin rashes and haemorrhagic manifestations in 1.5% cases each. Anemia, leucopenia, and thrombocytopenia were noted in 85(79.5%), 50(46.2%) and 78(72.8%) of patients, respectively. The associated diseases were noted 42(39.2%) deaths. The hospitalisation days were 6.3 days/patient. High grade fever, muscle pain, vomiting anemia leucopenia with lymphocytosis, thrombocyt-openia were detected commonly, while skin rashes, shock and haemorrhagic diathesis were rare complication of primary dengue fever cases looked, The associated clinical condition i.e. , malaria, enteric fever etc. should be looked, they might be responsible for complications in primary dengue fever cases.

Keywords: Clinico-haematological, Dengue, Fever.

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Corresponding Author

Naimish Patel

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