Title: Histopathology of Urothelial Neoplasms-Teritiary Care Centre Study

Authors: Dr Karra Shilpa, Dr Rejani Komalam, Dr Madhukumar Ramakrishna

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i2.03

Abstract

Introduction: Tumors of the bladder are one of the most common urological lesions encountered in clinical practice. Cancer of the urinary bladder is the 7th most common cancer worldwide. Urothelial cancer has a propensity of divergent differentiation9. Urinary bladder lesions, non-neoplastic and neoplastic, are collectively responsible for significant morbidity and mortality. It is important to identify the neoplasm early and its invasive nature as it determines the prognosis of the patient.

Aims & Objectives

1.      To study the histopathological spectrum of urothelial neoplasms

2.      To determine age &sex distribution of urothelial tumors.

Methods: A One year study, from June 2015 to July 2016, of urothelial neoplasms was carried out in Department of pathology Mysore medical college &Research institute. Relevant clinical history of the cases were noted.

Results: 30 cases were studied in the time period. Among the 30 cases studied most common was invasive urothelial carcinomas (40%), followed by 30% papillary urothelial carcinoma low grade ,10% papillary urothelial carcinoma high grade and 20% cases were diagnosed was papillary urothelial neoplasm of low malignant potential(PUNLMP) .53.33% of the total cases were in the age group of 51-70years. 96.66% were male patients.

Conclusion: Bladder cancer has become common now a days, which are more common in the elderly age with prevalence in males. Histopathological analysis of biopsy material is the mainstay for cancer diagnosis and treatment

 

Keywords: Urothelial neoplasm, Histopathological spectrum, Bladder tumor.

References

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9.      Eble JN, Sauter G, Epstein JI, et al., editors. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. IARC Press; Lyon: 2004. World Health Organization Classification of Tumours; p. 359.

10.  Laisram RS, Kipgen P, LaishramS, Khuraijam S, Sharma DC.Urothelial tumors of the urinary bladder in Manipur: A histopathological perspective. Asian Pac J Cancer Prev.2012;13(6):2477-9.

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Corresponding Author

Dr Karra Shilpa

Address: #574/A, North East of N R Mohalla, Mysore 570007

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Contact number: 9060500075