Title: A Retrospective Study on Risk Factors and Clinical Presentation of Ectopic Pregnancy

Authors: P. Sujata, Janmejaya Sahoo, Jagadish Hansa, Gangadhar Sahoo

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i1.122

Abstract

Introduction: The objectives are to study the incidence, clinical presentations and risk factors of all cases of ectopic pregnancy that presented to our centre over a period of five years.

Method: A retrospective study was done on all cases of ectopic pregnancies who were admitted to the O&G dept. of Institute of Medical Sciences and SUM Hospital, under Siksha ‘O’ Anusandhan University, Bhubaneswar from January 2009 to December 2013. Information was obtained from the case notes, theatre and labour ward registers.

Results and Discussion: A total of 200 cases of ectopic pregnancy were diagnosed. The total no. of deliveries which took place during the study periods were 6084. The incidence of ectopic pregnancy in the present study was 3.2%. Risk factors were present in 35% of cases. Majority of the cases were ampullary pregnancies (66.5%). Ectopic pregnancy presented with diverse symptoms. Majority of the cases (39%) presented with pain abdomen. Abdominal pain is due to peritoneal irritation as most of the cases had rupture ectopics  at the time of presentation. Death occurred in 3 cases which were mainly due to delay in referral.

Conclusion: The incidence of ectopic pregnancy in our centre was 3.2%. The most common identifiable risk factor was PID.

Keywords: PID, Ampulla, infertility, abortion, ectopic.

References

1.      Dutta DC. Haemorrhage in Early pregnancy. In: Koner H, editor. Textbook of Obstetrics. Revised reprint of 7thedition: Nov. 2013. Pg 177- pg. 190

2.      Igwegbe AO, Eleje Gu, Okpola BC. An appraisal of the management of ectopic pregnancy in a Nigerian Tertiary Hospital. Ann Med Health Science Res. 2013; 3(2): 166-170.

3.      Udigwe GO, Umeononihu OS, MbachuII. Ectopic pregnancy: A 5 year review of cases at Nnemdi Azikiwe Univerisity Teaching Hospital (NAUTH) Nnewi. Niger Med J. 2010; 51:160-3.

4.      Bouyer J, Coste J, Shojaei T, Jean-Luc P, Fernandez H, Gerband L, Job-Spira N. Risk Factors for Ectopic Pregnancy: A Comprehensive Analysis Based on a Large Case-Control, Population-based Study in France. Am J. Epidemiol. 2003; 157 (3): 185-194.

5.      Maifa Abdulaziz Al-Turki, ISRN Obstet-rics and Gynaecology Vol 2013 (2013), http//dx.doi.org/10.1155/2013/97251.

6.      Hamura NN, Bolnga JW, Wangnapi R, Horse AW, Rogerson SJ, Unger HW. The impact of tubal ectopic pregnancy in Papua New Guinea – a retrospective case review. 2013. http//www.biomedcentral.com/14-71-2393/13/86.

7.      Rashmi A Gaddagi and AP Chandrashekhar, A clinical study of ectopic pregnancy. Journal of clinical and Diagnostic Research. 2012, 6(5): 867-869.

8.      De Muylder X: Ectopic pregnancy in Ziwbabwe. Int.J Gynaecol. 1991, 35 (1):55-60.

9.      Amoko DH, Buga GA. Clinical Presentation of ectopic pregnancy in Transkei, South Africa. East Africa. Med J. 1995, 72 (12): 770-773

10.  V.L Holt, J.R Daling, L.F Voigt et al. Induced abortion and the risk of subsequent ectopic pregnancy. American Journal of public health. 1989. 79(9); 1234-1238.

11.  Comprehensive Gynaecology, 3rd edition, Missouri, St. Louis: Mosby 1997; 432.

12.  Peterson HB, Xca Z, Hughes J H, Wilcon LS, Tylor LR, Trussel J. The risk of ectopic pregnancy after tubal sterilization. N Engl J Med. 1997; 336: 762-7.

13.  Nwanodi O, Khulpateea N. The preoperative diagnosis of primary ovarian pregnancy. Natl Med Asso. 2006, 98(5); 796-8

14.  Anorlu RI, Oluwole A, Abudu OO, Adebajo S. Risk factors for ectopic pregnancies in Lagos, Nigeria. Acta Obstet Gynaecol Scand. 2005; 25; 596-8.

15.  Edmonds K, editor. Dewherst’s Textbook of Obstetrics and gynaecology. 7th ed. Oxford. London: Blackwell science ; 207. Pp 106-16

16.  Orji EO, Fasubaa OB, Adeyemi B, Dare FO, Onwardegwu U, Ogunniyi SO. Mortality and morbidity associated with misdiagnosis of ectopic pregnancy in defined Nigerian population. J Obstet Gynacol. 2002; 22: 548-50.

17.  Bag TS, Saha DP, Dasgupta N, Sarkar M, Mandal SK, Mondal T, Saha SK. Time Trends in ectopic pregnancy over a decade- a retrospective hospital based study. J Indian Med Assoc. 2012, 109 (10): 727-729.

18.  Ghararo EP, Igbafe AA. Ectopic pregnancy revisited in Benin city, Nigeria: analysis of 152 cases. Acta Obstet Gynecol Scand. 2002, 81(12) 1139 – 1143.

19.  Stovall TG, Ling Fw, Gray LX. Single dose methotrexate for treatment of ectopic pregnancy. Obstet Gyanecol. 1991; 77(5): 754-7.

20.  Menon S, Colinis J. Barnhart KT. Establishing a human chronic gonadotr-ophic cut off to guide Methotrexate treatment of ectopic pregnancy a syste-matic review. Fertilsteril. 2007; 87(3): 481-4.

21.  Ikme AC, Ezegwki HU. Morbidity and mortality following tubal ectopic pregnancy Enugu Nigeria. J Obstet Gynecol. 2005; 25:596-8.

22.  Aboyeyi AP, Fawole AA, Ijaiya Ma, Trends in Ectopic Pregnancy in Ilorin, Nigeria. Nigerian J Surg Res. 2002; 4:6-11.

23.  Gazvani MR. Modern management of Ectopic pregnancy. Br. J Hosp Med. 1996. 56: 597- 9.

Corresponding Author

Dr P. Sujata

Associate Professor, Dept. Of O&G

IMS &SUM Hospital, Bhubaneswar

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