Title: Effect of Antihypertensive Drugs on Glucose Tolerance and Lipid Profile in Hypertensives With and Without Diabetes Mellitus
Authors: Dr M. Saboora Beegum, Dr C.Edwin Emperor, Dr Suja.S.R
DOI: https://dx.doi.org/10.18535/jmscr/v5i1.83
Abstract
Introduction
Diabetes is the most common endocrine disease. It is a heterogeneous primary disorder of carbohydrate metabolism with multiple etiologic factors that generally involve absolute or relative insulin deficiency or insulin resistance or both. All causes of Diabetes Mellitus lead to hyperglyc-emia, which is the hail mark of this disease syndrome.
In all types of Diabetes Mellitus, the glucose tolerance is reduced. The theory of glucose tolerance is that a normal person should be able to remove a glucose load from plasma with in a short specified period of time. If for some reason he is unable to do so, the plasma concentration remains elevated longer than normal and the patient is said to have reduced glucose tolerance.
References
1. Hamilton BP Am. J. of Kidney Disease. 1990 Oct; 16(4 Suppl 1); p 20-9 1986 Mark C Houston
2. Treatment of hypertension in Diabetes Mellitus American Heart J. 118 : 819-829, 1989.
3. Effect of Beta Blocker on lipid profile Am. Heart J. 109 : 1192-6, 1985.
4. Jc Fruchart, J Shepherd Clinical Biochemistry, Principles Methods and application. Human Plasma Lipoprotfien; Dys-lipoproteinemoia in D M, P174
5. Antihypertensive drugs and blood lipids J. Human Hypertension, 4 Suppl. 3 ; 17, 1990 Octo
6. Peter E Pool. Progress in Cardio Vascular disease Vol 35 No.l, 1993
7. Michael W Steffes Clinical Chemistry 32 : 10(B), 1986.
8. Classification of Diabetes Mellitus, W.H.O., 1985
9. Detection and Management of lipid disorders in Diabetes consensus statement. Diabetes care Vol. 18, Supp I Jan 1995.
10. Drury. PL Diabetes and arterial hyperte-nsion Diabetologia. 24 : 1-9, 1983
11. P, Lombrail. P, Eschwego. E, Canirel. J Prevalence do hypertension arterielle chez le diabetigue, Influence des traitements antihypertenseurs sur le controle metaboligue Arch Mai Coeur 76 : 169-71, 1983
12. Havlik. RJ, Hubert. HB, Fabsitz. RR, Feinleib. M Weight and hypertension Ann Intern Med. 98 : 855-859, 1983
13. Parving HH, Anderson AR, Smidt UM, Christiansen JS, Oxenboll, Svendsen PA Diabetic nephropathy and arterial hypertension : the effect of antihypertive tt in diabetes 32 (Supp 2) 83-87, 1974.
14. Garcia. MJ, Mc Namara. PM, Gordon. T, Kannel. WB Morbidity and mortality in diabetes in the Framingham population Diabetes 23 : 105-114, 1974