Title: Comparative Evaluation of Bupivacaine Versus Ropivacaine Epidurally in Obstetrical Surgeries (LSCS): A Clinical Study
Authors: Prashant Mishra, Navneet Goyal, Pragati Divedi, Manoj Kumar, Divya Pandey, Dheer Singh
DOI: http://dx.doi.org/10.18535/jmscr/v3i8.61
DIDS : 08.2015-XXXXXXX
Background: A double blind prospective and randomized study was carried out in our institute to compare the anaesthetic effects of Ropivacaine and Bupivacaine epidurally in elective Lower Segment Caesarean Section (LSCS). Method: A total of 50 patients aged 18-30 years of American Society of Anesthesiology (ASA) grade 1and 2, scheduled for elective LSCS under epidural block ,were enrolled for the study.Patients were divided into two groups of 25 each. Group 1 received 0.5% 15 ml Bupivacaine and group 2 received 0.5% 15 ml Ropivacaine. Heart Rate (HR), Mean Artery Pressure (MAP),SPO2, Respiratory Rate, Sensory Block, Motor Block, Mat-ernal and Fetal outcomes and Blood loss were observed and recorded throughout the study period at regular intervals. At the end of research project data’s were compiled systematically and were subjected to statistical analysis using student t-test. Value of p<0.05 is significant and p<0.01 as highly significant. Results: No significant difference seen in both the groups for demographic characteristics, SPO2, RR,HR, MAP sensory and motor block and materno-fetal outcome. No significant difference seen for side effects and complications in both the groups. Conclusion: Ropivacaine and bupivacaine given epidurally in the same concentration and volume provided similar and effective anaesthesia in patients undergoing elective LSCS. Key Worlds: Ropivacaine, Bupivacaine, Epidural, Elective LSCS 1. Alberg G. Toxicological and local anaesthetic effects of optically active isomers of two local anaesthetic compounds.Acta Pharmacol Scand 1972;31:273-86. 2. Rutten AJ, Nancarrow C,Mather LE,Ilsely AH, Runciman WB,Upton RN. Haemodynamic and central nervous system effects of intravenous bolus doses of Lidocaine,Bupivacaine and Ropivacaine in sheep.Anesth Analg 1989;69:291-9. 3. 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