Title: Weber`S Syndrome: A Rare Manifestation of CNS Toxoplasmosis in HIV/AIDS-A Case Report

Authors: U S Mishra, C R Khatua , Suchitra Dash, Chandan Gantayat, Satya Kumar K

 DOI:  http://dx.doi.org/10.18535/jmscr/v3i8.53

DIDS : 08.2015-XXXXXXX

Abstract

Neurological illnesses are the most frequent and devastating complications of HIV infection and AIDS, which includes HIV dementia, tuberculoma, primary CNS lymphoma and toxoplasmosis. Toxoplasmosis accompanied with HIV infection is usually caused by reactivation of a chronic infection by this parasite causing encephalitis. Toxoplasmic encephalitis may present a subacute course or can be fatal if untreated.

Keywords:HIV, AIDS, Toxoplasmosis, Opportunistic Infection.

References

 1.      Alireza B,Behrooz H,Pauline H,Maryam M . Review of Toxoplasmic Encephalitis in HIV   Infection; a Case Study;Archives of Neuroscience. 2015 April; 2(2): e20891.

2.      Sreeramulu Diguvinti et al.Cerebral toxoplasmosis in HIV mimicking as primary CNS    lymphoma/tuberculoma:case report.International Journal of Research in Health Sciences..Jul-Sept 2014;Issue-3.

3.      Montoya JG,, Remington JS. Toxoplasma gondii. In: Mandell GL, Bennett JE, Dolin R, editor(s). Principles and Practice of Infectious Diseases. Philadelphia: Churchill Livingstone; 2000. p. 2858-2888.

4.      Luft BJ, Remington JS. Toxoplasmic encephalitis in AIDS. Clin Infect Dis. 1992;15(2):211-22.

5.      Navia BA, Petito CK, Gold JW, Cho ES, Jordan BD, Price RW. Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: clinical and neuropathological findings in 27 patients. Ann Neurol. 1986;19(3):224-38.

6.      Renold C, Sugar A, Chave JP, Perrin L, Delavelle J, Pizzolato G, et al. Toxoplasma encephalitis in patients with the acquired immunodeficiency syndrome. Medicine (Baltimore). 1992;71(4):224-39.

7.      Gray F, Gherardi R, Wingate E, Wingate J, Fenelon G, Gaston A, et al. Diffuse "encephalitic" cerebral toxoplasmosis in AIDS. Report of four cases. J Neurol. 1989;236(5):273-7.

8.      Porter SB, Sande MA. Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome. N Engl J Med. 1992;327(23):1643-8.

9.      San-Andres FJ, Rubio R, Castilla J, Pulido F, Palao G, de Pedro I, et al. Incidence of acquired immunodeficiency syndrome-associated opportunistic diseases and the effect of treatment on a cohort of 1115 patients infected with human immunodeficiency virus, 1989-1997. Clin Infect Dis. 2003;36(9):1177-85.

10.  Levy RM, Janssen RS, Bush TJ, Rosenblum ML. Neuroepidemiology of acquired immunodeficiency syndrome. J Acquir Immune Defic Syndr. 1988;1(1):31-40

11.  Koppen S, Grunewald T, Jautzke G, Gottschalk J, Pohle HD, Ruf B. Prevention of Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus infected patients: a clinical approach comparing aerosolized pentamidine and pyrimethamine/sulfad-oxine. Clin Investig. 1992;70(6):508-12.

12.  Schurmann D, Bergmann F, Albrecht H, Padberg J, Wunsche T, Grunewald T, et al. Effectiveness of twice-weekly pyrimethamine-sulfadoxine as primary prophylaxis of Pneumocystis carinii pneumonia and toxoplasmic encephalitis in patients with advanced HIV infection. Eur J Clin Microbiol Infect Dis. 2002;21(5):353-61.

13.  Kami kim, Lloyd  H K. Toxoplasma infection: Harrison`s Principles Of Internal Medicine .19th Edition.2015;(253):1398-1405.

Corresponding Author

C R Khatua

Assistant Professor

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.