Title: Gastric Carcinoma: A Clinical Study
Author: Dr Santosh M Patil
DOI: http://dx.doi.org/10.18535/jmscr/v3i8.32
DIDS : 08.2015-XXXXXXX
This is a clinical study on 41 gastric neoplasm subjects diagnosed by upper gastrointestinal endoscopy. These patients were evaluated with set of questions and monitored for clinical presentation with risk factors till the treatment. Forty one cases of carcinoma stomach which were serially monitored for signs and symptoms. It was noted patients had Dyspepsia in 18(43.9%) patients, pain abdomen in 37(90.2%), vomiting in 35(85.4%), loss of weight and loss of appetite in 39(95.1%) and mass per abdomen in 1 patient (2.4%)Pallor noted in 32 (78%) patients, mass palpable in 17 (41.5%) patients, liver palpable in 8 (19.5%) patients, ascites in 10 (24.4%) patients and Virchow’s node positive in 6 (14.6%) patients. Smoking and alcohol consumption were predisposing risk factors with 21 (51.2%), 17 (41.5%) respectively. This study helps to identify the common symptoms and signs of the Gastric cancer, which can be picked up by thorough clinical evaluation, which also helps patients to diagnose and subject to accurate treatment immediately thus reducing the morbidity and mortality. Key Words: Gastric carcinoma; symptoms; diagnosis. 1. T.W.Sadler: Digestive system. In, Susan katz (eds): Langman’s medical embryology, 8thEdn. Lippincott, William and wilkin’s 2000; 270-76. 2. Rao DN, Ganesh B. Estimate of cancer incidence in India in 1991. Indian J Cancer 1998; 35:10-8. 3. Yeole BB. Trends in cancer incidence in esophagus, stomach, colon, rectum and liver in males in India. Asian Pac J Cancer Prev 2008; 9:97-100. 4. Satyanarayana L, Asthana S. Life time risk for development of ten major cancers in India and its trends over the years 1982 to 2000. Indian J Med Sci 2008; 62:35-44. 5. Rastogi T, Devesa S, Mangtani P, et al. Cancer incidence rates among South Asians in four geographic regions: India, Singapore, UK and US. Int J Epidemiol 2008; 37:147-60. 6. Lawrence H, Bannister, Martin M, Berry: Gastrointestinal system in Gray’s Anatomy 39thEdn. Churchill livingstone 2008.1140- 1150. 7. Mercer DW, Liu TH, Castaneda A: Anatomy and physiology of the stomach, in Zuidema GD, Yeo CJ (eds): Shackelford's Surgery of the Alimentary Tract, 5th ed., Vol. II. Philadelphia: Saunders, 2002, p 3. Copyright Elsevier. 8. David W. Mercer M.D.Emily K. Robinson M.D: Stomach in Sabiston Textbook of Surgery, 17th Edn. Saunders company 2004.1265-1312. 9. Moody F, McGreevy J, Miller T: Stomach. In Schwartz SI, Shires GT [eds]: Principles of Surgery, 5th ed. New York,McGraw-Hill, 1989. 10. Hermanek P, et al (eds): TNM Atlas: Illustrated Guide to the TNM/pTNM Classification of Malignant Tumours, 4th ed. Berlin: Springer-Verlag, 1997, p82–83. 11. Eslick GD. Helicobacter pylori infection causes gastric cancer? A review of the epidemiological, meta-analytic, and experimental evidence. World J Gastroenterol 2006; 12:2991-9. 12. Uemura N, Okamoto S, Yamamoto S, et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 2001; 345:784-9. 13. Huang JQ, Sridhar S, Chen Y, et al. Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer. Gastroenterology 1998; 114:1169-79. 14. Schistosomes, liver flukes and Helicobacter pylori. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, 7-14 June 1994. IARC MonogrEvalCarcinog Risks Hum 1994; 61:1-241. 15. Khan MI, Baqai MT, Bukhari M, Hashmi RI: Gastric carcinoma: 5 years survival after gastric surgery. J Pak Med Assoc 2005, 55:158–160. 16. Safaee A, Moghimi-Dehkordi B, Fatemi SR, et al. Clinicopathological Features of Gastric Cancer: A Study Based on Cancer Registry Data. IJCP 2009; 2:67-70. 17. Sasagawa T, Solano H, Mena F. Gastric cancer in Costa Rica. GastrointestEndosc 1999; 50:594-5; discussion 595-6. 18. Yao JC, Tseng JF, Worah S, et al. Clinicopathologicbehavior of gastric adenocarcinoma in Hispanic patients: analysis of a single institution’s experience over 15 years. J ClinOncol 2005; 23:3094-103. 19. Sadjadi A, Malekzadeh R, Derakhshan MH, et al. Cancer occurrence in Ardabil: results of a population-based cancer registry from Iran. Int J Cancer 2003; 107:113-8. 20. Kong SH, Park DJ, Lee HJ, et al. Clinicopathologic features of asymptomatic gastric adenocarcinoma patients in Korea. Jpn J ClinOncol 2004; 34:1-7. 21. Medina-Franco H, Heslin MJ, Cortes-Gonzalez R. Clinicopathological characteristics of gastric carcinoma in young and elderly patients: a comparative study. Ann SurgOncol 2000; 7:515-9. 22. Rao DN, Ganesh B, Dinshaw KA, et al. A case-control study of stomach cancer in Mumbai, India. Int J Cancer 2002; 99:727-31. 23. Eskandar H, Hossein SS, Rahim M, et al. Clinical profile of gastric cancer in Khuzestan, southwest of Iran. World J Gastroenterol 2006; 12:4832-5. 24. Plummer JM, Gibson TN, McFarlane ME, et al. Clinicopathologic profile of gastric carcinomas at theUniversity Hospital of the West Indies. West Indian Med J 2005; 54:364-8. 25. Kelley JR, Duggan JM. Gastric cancer epidemiology and risk factors. J ClinEpidemiol 2003; 56:1-9. 26. Joseph B Mabula, Mabula D Mchembe et al Gastric cancer at a university teaching hospital in northwestern Tanzania: a retrospective review of 232 cases. World Journal of Surgical Oncology 2012, 10:257 Abstract
References