Title; Disseminated Intravascular Coagulation: As Presenting Feature in Patients with Systemic Lupus Erythematosus - Two Case Reports
Authors: Mishra U S, Khatua C R, Patro D, Arun S V, Satya K
DOI: http://dx.doi.org/10.18535/jmscr/v3i8.24
DIDS : 08.2015-XXXXXXX
There are different types of initial manifestation of systemic lupus erythematosus (SLE) like rash, oral ulcers, joint pain, anaemia and repeated abortions1,2,3 but presenting with fever altered sensorium4,5, hepatopathy, hypotension and bleeding disorder9,10 can be rare initial clinical presentations in both new and diagnosed patients of SLE. We present two patients of SLE with this rare manifestation. Key Words: Systemic lupus erythematosus (SLE), Disseminated intravascular coagulation (DIC), multiorgan dysfunction syndrome (MODS). 1. D'Cruz DP, Khamashta MA, Hughes GR. Systemic lupus erythematosus. Lancet. 2007;369:587–96. 2. Zoma A. Musculoskeletal involvement in systemic lupus erythematosus. Lupus. 2004;13:851–853. 3. Chan MT, Owen P, Dunphy J, et al. Association of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC Class II alleles in systemic lupus erythematosus. J Rheumatol. 2008;35:77–83. 4. Carrol BT, Anfinson TJ, Kennedy JC, Yendrek R, Boutros M, Bilon A. Catatonic disorder due to general medical conditions. J Neuropsychiatry Clin Neurosci. 1994;6(2):122–133. 5. American College of Rheumatology. The American College of Rheumatology Nomenclature and case definitions for neuropsychiatric lupus syndromes. Arthritis Rheum. 1999;42(4):599–608. 6. Mac DS, Pardo MP. SLE and Catatonia: a case report. J Clin Psychiatry. 1983;44(4):155–156. 7. Daradkeh TK, Nasrallah NS. Lupus Catatonia: a case report. Pharmatherapeutica . 1987;5(2):142–144. 8. Lanhaml JG, Brown MM, Hughes GR. Cerebral systemic lupus erythematosus presenting with catatonia. Postgrad Med J. 1985;61(714):329–330. 9. Tanaka M1, Kobayashi S,et al. Disseminated intravascular coagulation in a patient with systemic lupus erythematosus with lupus anticoagulant. Intern Med. 1993 Jun;32(6):513-7. 10. Shimamoto Y1, Suga K, Ohta A, Yamaguchi M.Risk factors for the development of acute disseminated intravascular coagulation in patients with systemic lupus erythematosus. Clin Rheumatol. 1995 Mar;14(2):176-9. 11. Disseminated Intravascular Coagulation (DIC). (n.d.). The Merck Manuals. Retrieved March 18, 2012. 12. Dr. Y. Shimamoto, K. Suga, A. Ohta,M. Yamaguchi.Risk factors for the development of acute disseminated intravascular coagulation in patients with systemic lupus erythematosus ,Clinical Rheumatology.March 1995, Volume 14, Issue 2, pp 176-179. Abstract
References