Title: A Study of Histopathological Pattern of Ovarian Neoplasms and their Age Distribution in A Tertiary Care Hospital of South India
Authors: Dr Vinay Kumar R, Dr B Rammohan Rao, Dr Epari Sanjeeva Rao
DOI: http://dx.doi.org/10.18535/jmscr/v3i9.09
Objectives: The aim of the study was to know the histopathological pattern of ovarian neoplasms and their distribution in various age groups in a tertiary care hospital. Materials and methods:80 cases of ovarian specimens received from Department of Obstetrics and Gynecology, local nursing homes and hospitals were studied in Department of Pathology of a tertiary care hospital for a period of 1 year from May 2014 to April 2015. The ovarian tumours were classified according to WHO classification and the age distribution was noted. Results: Eighty cases of ovarian tumors were studied during this period. Benign tumors comprised 91.25% and malignant tumors were 8.75%. Surface epithelial tumor was the commonest variety accounting for 83.75%, followed by germ cell tumor (13.75%) and sex cord stromal tumors were least common comprising 2.5 % of all ovarian neoplasms. No metastatic tumor or tumors with borderline malignancy were seen. Serous cystadenoma was the commonest tumor (49.31%) seen in 30-50 years age followed by Mucinous cystadenoma (32.87%) seen in 30-60 years age. Mature cystic teratoma comprised 81.8% of germ cell tumours seen in 20 -40 years age. Fibrothecomas were seen above 50 years of age. Among the malignant tumors, malignant surface epithelial tumors were the commonest seen above 40 years. Conclusion: Benign ovarian tumors are seen more common than malignant tumors. The most common benign ovarian neoplasm is Serous cystadenoma and the commonest malignant neoplasm is Mucinous cystadenocarcinoma. Benign ovarian tumours are seen in 20 to 50 years of age and Malignant tumors are seen after 40 years of age. Keywords: Ovarian tumors, Surface epithelial tumors, Serous cystadenoma, Germ cell tumors, Sex cord stromal tumors. 1. National Cancer Institute 2005. SEER cancer statistics review (1975-2002). Ovarian epithelial cancer (PDG): Treatment health professionals. J National Cancer Institute. Vol 98. 2. Prat J. Female reproductive system. In: Damjanov I, Linder J, eds. Anderson’s pathology. St. Louis,Missouri: Mosby, 1990;2231-309. 3. Rosai J .Ovary. In: Rosai and Ackerman’s surgical pathology 10th Ed. Missouri: Elsevier; 2011.vol2.p.1553-1635. 4. Louisa WY, Dainty G, Scott R, et al. Gynecological malignancies in women aged more than 25 years.Am J Obstet Gynecol 2005;105:1405-9. 5. Yasmin S, Yasmin A, Asif M. Clinicohistological pattern of ovarian tumors in Peshwar region. J Ayub Med Coll Abbottabad 2008; 20(4):11-13. 6. Jha S, Karki S. Histological pattern of ovarian tumors and their age distribution. Nepal Med Coll J 2008; 10(2):81-85. 7. Pilli GS, Suneeta KP, Dhaded AV, Yenni VV. Ovarian tumors: a study of 282 cases. J Indian Med Assoc 2002; 100:420-24. 8. Jha R, Karki S. Histological pattern of ovarian tumors and their age distribution. Nepal Med Coll J 2008; 10: 81-85. 9. Maheshwari V, Tyagi SP, Saxena K, Tyagi N, Sharma R, Aziz M, Hameed F. Surface epithelial tumors of ovary. Indian J Pathol Microbiol 1994 Jan; 37(1):75-85. 10. Thanikasalam K, Ho CM, Adeed N, Shahidan N, Azizah WK. Pattern of ovarian tumors among Malaysian women at General Hospital, Kuala Lumpur. Med J Malaysia1992; 47:139-46. 11. Ahmad Z, Kayani N, Hasan SH, Muzaffar S, Gill MS. Histological pattern of ovarian neoplasm. J Pak Med Assoc 2000; 50:416-419. 12. Pradhan A, Sinha AK, Upreti D. Histopathological patterns of ovarian tumors at BPKIHS. Health Renaissance 2012; 10(2):87-97. 13. Tyagi SP, Maheswari V, Tyagi N, Saxena K, Sharma R, Hameed F. Solid tumours of the ovary. J Indian Med Assoc 1993; 91:227-230.Abstract
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