Title: Spectrum of Cytological Findings In Patients with Superficial Lymphadenopathy: A Five Year Retrospective Study
Authors: Dr Rajesh Gaur, Dr Poonam Woike
DOI: http://dx.doi.org/10.18535/jmscr/v3i10.37
Superficial lymphadenopathy is ranked among the most common clinical findings encountered in medical practice. Fine needle aspiration cytology (FNAC) is a veritable tool for the assessment and diagnosis of superficial lymph node enlargement. The aim of our study is to see the profile of superficial lymphadenopathy in our region and the role of FNAC in the definite diagnosis of cause of lymphadenopathy. In this 5 years study a total of 1188 patients with superficial lymphadenopathy were referred from the out patients clinics for cytological examination. FNAC was performed using 23 gauge needle attached to 20ml syringe. Aspirated materials were smeared into 2-3 slides which were stained with May Grunwald Giemsa (MGG) stain and using Dibutyl Phathalate Xylene (D.P.X) mountant were prepared for cytological examination. Five year data was collected and compiled into various categories. The cervical region was involved in most of the cases (90.15%) followed by the axillary region (6.98%) and lastly by inguinal region (2.3%). Tubercular lymphadenitis (53.9%) was the commonest cause of lymphadenopathy followed by reactive lymphoid hyperplasia (28.8%), metastasis (13.4%) and lymphomas (2.86%). Squamous cell carcinoma (9.5%) followed by adenocarcinoma (3.9%) were the most frequent metastatic tumors. FNAC is a useful diagnostic tool in the management of patients presenting with lymphadenopathy and should be considered before more invasive and costly procedures are performed, particularly in developing countries. Keywords: Lymphadenopathy , FNAC, Diagnosis, Malignancy. 1. Darnal HK, Karim N, Kamini K, Angela K (2005). The Profile of Lymphadenopathy in Adults and Children. Med J Malaysia, 60, 590-8. 2. Singh K, Dubey VK, Khajuria R.Diagnostic accuracy of fine needle aspiration cytology when compared to histopathology. J Cytol 2003; 20: 22-7 3. Tilak V, Dhaded AV, Rain R. Fine needle aspiration cytology of head and neck masses. Indian J Pathol Microbiol 2002; 45: 23-30 4. Bhuyan MAH, Fakir MAY, Hossain ABMT, Huq AHMZ, Gupta S (2008). Role of Fine needle aspiration cytology in the diagnosis of cervical lymphadenopathy. Bangladesh J Otorhinolaryngol, 14, 63-5. 5. Ahmad SS, Akhtar S, Akhtar K, Naseem S, Mansoor T (2005). Study of fine needle aspiration cytology in lymphadenopathy with special reference to Acid-fast staining in cases of tuberculosis. JK Science, 7, 1-4. 6. Khan AH, Hayat AS, Baloch GH, et al (2011). Study on the role of fine needle aspiration cytology in cervical lymphadenopathy. World Applied Sci J, 12, 1951-4. 7. Fatima S, Arshad S, Ahmed Z, Hasan SH (2011). Spectrum of Cytological Findings in Patients with Neck Lymphadenopathy-Experience in a Tertiary Care Hospital in Pakistan. Asian Pac J Cancer Prev, 12, 1873-5. 8. Steel BL, Schwartz MR, Ibrahim R (1995). Fine needle aspiration biopsy in diagnosis of lymphadenopathy in 1,103 patients. Acta Cytolo, 39, 76-81. 9. Mitra S, Ray S, Mitra PK (2011). Fine needle aspiration cytology of supraclavicular lymph nodes: Our experience over a three-year period. J Cytol, 28, 108-10. 10. Khajuria R, Goswami KC, Singh K, Dudey VK (2006). Pattern of lymphadenopathy on fine needle aspiration cytology in Jammu, JK Sci, 8, 145-9. 11. Hirachand S, Lakhey M, Akhter J, Thapa B (2009). Evaluation of fine needle aspiration cytology of lymph nodes in Kathmandu Medical College, Teaching hospital. Kathmandu Univ Med J, 7, 139-42. 12. Wilkinson AR, Mahore SD, Maimoon SR (2012). FNAC in the diagnosis of lymph node malignancies: A simple and sensitive diagnostic tool. Ind J Med Pead Oncol, 33, 21-4. 13. Pandit AA, Candes FP, Khubchandani SR (1987). Fine needle cytology of lymphnodes. J Postgrad Med, 33, 134-6. 14. Nidhi P, Sapna T, Shalini M, Kumud G (2011). FNAC in tuberculous lymphadenitis: Experience from a tertiary level referral centre. Indian J Tub, 58, 102-7. 15. Dhingra V, Misra V, Mishra R, Bhatia R, Singhal M (2010). Fine needle aspiration cytology (FNAC) as a diagnostic tool in Paediatric lymphadenopathy. J Clin Diagn Res, 4, 2452-7. 16. Martin DA, Janes OA, Allen SL, John nd EN. Clinical Oncology 2 Ed. London (UK): Churchill Livingstone Inc. 2000:2620-9Abstract
References