Seroprevalance of Hepatitis B and Hepatitis C Virus Infection among HIV Positive Individuals From Tertiary Care Hospital in Allahabad District of North India

Title: Seroprevalance of Hepatitis B and Hepatitis C Virus Infection among HIV Positive Individuals From Tertiary Care Hospital in Allahabad District of North India

Authors: Monica Singh, Dakshina Bisht, Vatsala Misra, Amod Kumar, Sanjay Kumar, Arindam Chakraborty

DOI: http://dx.doi.org/10.18535/jmscr/v3i10.12

Abstract

The study was designed to assess the hepatitis B virus and hepatitis C virus prevalence in HIV infected patients in tertiary care hospitals. A cross sectional study of prevalence and risk factors of HBV and HCV co-infection in HIV patients was conducted. A total of 1716 patients of all ages enrolled for ART Therapy at ART centre were screened for the presence of HBs Ag and anti-HCV antibodies by ELISA technique. In 1716 HIV infected patients, 56(3.26%) were positive for HBV and 16(0.9%) for HCV and 1(0.05%) was positive for dual co-infection (HBV/HCV). Heterosexual contact were the acquisition of HBV/HIV co-infection in 75% of patients and other modes like MSM 1.78%, Injective drug users 5.35%, Blood transfusion 1.78%, Mother to child 3.57%, Probable unsafe injection 1.4%, unknown 8.92%, commercial sex worker 0% while in HCV/HIV co-infection 50% acquisition is by heterosexual contact and second most common risk factor was injective drug users 43.7% in seropositive patients. The principal routes for HIV transmission are similar to HBV and HCV infection. In our study the heterosexual contact and Injective drug users were found to be major risk groups. The prevalence of HBV and HCV is low among HIV patients in Allahabad as compared to other studies of North India. However it would be advisable to screen for these viruses in all the HIV infected individuals and their sexual partners at the earliest.

Key words: Seroprevalence, HBV, HCV, HBV HCV India, co-infection, HIV.

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Corresponding Author

Monica Singh

PhD Scholar, Microbiology Department, Santosh Medical College, Deemed to be University, Ghaziabad

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