Title: Prevalence of Asymptomatic Peripheral Vascular Disease in Patients with Type-2 Diabetes Mellitus by Colour Doppler Study and Correlation with Risk Factors and Myocardial Infarction

Authors:Goutham Vidyam, Dilip M Rampure, Nayan Patel, Sowmya Arapareddy

 DOI:  http://dx.doi.org/10.18535/jmscr/v3i11.46

Abstract

Background

Peripheral Arterial Disease (PAD) is a condition characterized by atherosclerotic occlusive disease of the lower extremities. While PAD is a major risk factor for lower-extremity amputation, it is also accompanied by a high likelihood for symptomatic cardiovascular and cerebrovascular disease, leading to an elevated risk of events, such as myocardial infarction (MI), stroke, and death. It has been reported that of those patients with PAD, over one-half of them are asymptomatic or have atypical symptoms. The current study is intended to study the prevalence of asymptomatic PAD in patients with DM-2 by Colour Doppler study and to correlate it  ischemic heart disease.

Aims And Objectives:

1.      To study the prevalence of asymptomatic peripheral artery disease in 40 patients with Type-2 Diabetes by Colour Doppler Study.

2.      To study the correlation of PAD with myocardial ischemia by Electrocardiography.

Material And Methods: A total number of 40 patients of DM-2 patients who had no history of symptomatic  peripheral vascular disease attending outpatient department at Mamata General Hospital, Khammam, during the period of August 2013 to August 2014, were selected randomly and Colour Doppler of peripheral vessels performed .Cross sectional analysis regarding risk factors and electrocardiographic changes were done

Results: Prevalence of asymptomatic peripheral vascular disease was found to be  25% which is significant. 40% of patients with PAD were found to have myocardial ischemia by electrocardiogram. 80% of patients with peripheral artery disease, identified by Colour Doppler study, have normal peripheral pulses on clinical examination suggesting more sensitivity of Colour Doppler examination.

Conclusion: The prevalence of asymptomatic PAD in DM-2 was found to be significant (25%)

 Myocardial ischemia suggested by electrocardiogram was found to have strong positive correlation with the development of PAD (P=0.040, Significant)

80% of patients with PAD, identified by Colour Doppler study, have normal peripheral pulses on clinical examination suggesting more sensitivity of Colour Doppler study.

Key Words: Diabetes mellitus, peripheral artery disease, colour doppler, myocardial infarction.

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Corresponding Author

Goutham Vidyam

Post Graduate, Department of General Medicine