Title: Comparative Study of Oxidant Status and Lipid Profile in Vegetarians and Fish Eaters
Authors: Dr N. Viswabharathi*, Dr S.R.Manjula, K.Siddhartha
DOI: http://dx.doi.org/10.18535/jmscr/v3i11.10
Atherosclerosis was the leading cause of death and disability in the developed world. Habitual consumption of moderate amount of fish was associated with reduced mortality from coronary heart disease. However the beneficial effects of fish enriched diet seems contradictory due to susceptibility of the Poly Unsaturated Fatty Acid in them to oxidation; it was also acclaimed that vegetarians in general will have low serum cholesterol and a better anti oxidant status than fish eaters. In view of this a comparative study of oxidant status and lipid profile was done in vegetarians and fish eaters. This study enrolled 50 vegetarians and 50 fish eaters of age 35-55 years. Statistical Analysis by the students “T” Test or Mann Whitney “U” Test was applied depending upon the nature of the data. Pearson’s correlation co efficiencies (r value) were used to compare the correlations. It showed significant difference in HDL-C levels among fish eaters when compared to vegetarians; this study showed no significant difference in the lipid peroxide levels and the other lipoproteins. The correlation of malondialdehyde with HDL-C was negative in the vegetarians and weakly positive in the fish eaters. LDL-C showed a positive correlation with MDA in both the groups. Triglycerides showed a positive correlation with MDA and correlation was strong in fish eaters. Keywords= Atherosclerosis, Lipid profile, Oxidants, Antioxidants, Nutrients in fish. 1. Bang HO Dyberg J. (1972) Plasma Lipids and Lipo protein s in Green lands West Coastal 192, 85-94. 2. Bang HO Dyberg J. (1972) Plasma Lipids and Lipo proteins in Green lands West Coastal 200, 69-73 3. Sack FM, Wood PG, Kosh EH 1984, Stability of BP in Vegetarians receiving Dietary protein supplement HDN 6 199 -201 4. Ester Banner H, Chesseman KH, 1990 Determination of Aldehyde lipid per oxidation products, malondialdehyde, and forehydroxy nonal methods in enzymology, Academic press, 186, 407-21 5. Harman D, (1994) Free radical theory of aging increasing the functional life span. Ann NY Acad Sci. 717 para 1-15. 6. Denham Harman (1956): Aging a Theory based on free radical and radiation Chemistry, Journal of gerontology. 11 (3) Pg. 298-3007. 7. Mohammad A .(2002) ; Oxidative steress and experimental carcinogenesis. Ind.J.Exp.Biol.40:p656-667 8. Wiseman H and HAlliwellB(1996); Damage to DNA by reactive oxygen species ;Role of inflammatory diseases and progression to Cancer.Biochem. J.313:P17-29 9. Allain C.C. clinichem 20, 470 (1974). 10. Bustein, M. etal (1970) J. lipid res. 17:583 11. Jacobe, N.J., Van Demark, P.J. (1960) arch biochem. biophys. 88,250 12. tietz fundamentals of clinical chemistry sixth Edition : Edited by carl A. Burtis, Edward R. Ashwood David E. Bruns Chapter 23 : p 424. 13. lippin cott’s illustrated reviews 3rd Edition Chap. 26 Page 347. 14. Higdon J.V.Lice J.Morrow, JD,Ames BN Wander RC(2000) Supplimentation of postmenopausal woman with fish oil rich in EPA and DHA is not associated with grater in vivo lipid per oxidation compared with oils rich in oleate and linoleate as assessed by plasma Malondialdehyde and F2 –Isoprostanes: A.M.J.Clin Nutr 72,714-22. 15. Bhatta Charya J.Sri vastav DK(1993) Serum malondialdehyde in relation to Lipademic status and Atherogenic index :Indian jour of Clinical Bio 8:12-15. 16. OHARA Y.Peterson TE Harrison DG(1993) Hyper cholesterolemia increases endothelial superoxide anion production J CLIN.Invest91.2546-51. 17. Meydani M . Evans W J Handelruan G (1993) Protective effect of vitamin E on exercise induced oxidative damage in young and older adults AMJ Physiol.264: 992 –8 18. Piche LA : Draper HH cole PD (1988) malondialdehyde excretion by subject consuming Cod liver oil Vs a concentration of N3 fatty acids: Lipids 23:370-1 19. Mi Kyung Kim,1 Sang Woon Cho,1 and Yoo Kyoung Park 20. Long-term vegetarians have low oxidative stress, body fat, and cholesterol levels Nutr Res Pract. 2012 April; 6(2): 155–161Abstract
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