Title: Spectrum of Disorders Diagnosed By Bone Marrow Aspiration in Pediatric Population

Authors: Dr Aparajita Tomar, Dr RPS Chauhan, Dr R.K. Nigam

 DOI:  http://dx.doi.org/10.18535/jmscr/v3i12.24

Abstract

AIMS AND OBJECTIVES – To identify and analyse the most common hematological disorders diagnosed by doing bone marrow aspiration in pediatric patients.

MATERIAL AND METHOD – Bone marrow aspiration was done from Manubrium of the Sternum after injecting 2% xylocaine to the part in addition to sedation with diazepam. Bone marrow smears were prepared and stained with Leishman stain along with the simultaneous staining of the peripheral smears.  A complete hemogram including Hb%, PCV, Red cell indices, platelet count, total leucocyte count and differential leucocyte count was also done by Automated cell counter. Finally, the bone marrow and peripheral smears were examined manually under oil immersion.

CONCLUSION - In  this study it was found  that the  most  frequently  diagnosed  hematological  disorders on bone marrow aspiration  in  children  are Anemias  followed  by  Idiopathic  Thrombocytopenic  Purpura (ITP).  Hematological  disorders  are  more common  in  childhood  period  as  compared  to  late  adulthood. If taken individually then ITP cases outnumber the Anemia cases. Commonest  leukemia  in  children   is  Acute  Lymphoblastic  Leukemia (ALL)  and it  follows  the  Anemias  and  ITP.

KEYWORDS: Bone Marrow Aspiration, Anemia, Leukemia, Idiopathic Thrombocytopenic Purpura

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Corresponding Author

Dr Aparajita Tomar

MBBS, MD, Pathology, Dept of Pathology

Bundelkhand Medical College, Sagar, Madhya Pradesh, India

E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., Tel: 090396-32272 Fax: 07582-236270