Title: Prevalence of Dengue Fever in a Tertiary Care Center Experience
Authors: Dr Mamatha Shetty, Dr Urvashi,Dr Rajini Uday
DOI: http://dx.doi.org/10.18535/jmscr/v3i12.18
AIM: To study the maternal and perinatal outcomes in dengue fever pregnant women in a tertiary care center. METHOD: This was a retrospective study done in pregnant women with dengue fever. RESULTS: There were 75 pregnant women with confirmed dengue serology between January 2013 to October 2015 were included in the study. At the mean (SD) gestational age of 29+/-6 weeks. 36 patients (48%) were delivered by caesarean section, 45(60%) women needed SDP/FFP transfusion and there were no maternal deaths. 26patients (34.6%) of these 75 women had preterm deliveries and 32 neonates (42.6%) were admitted to neonatal intensive care unit. 19 women (25.3%) gave birth to low birth weight babies. There were five (6.6%) perinatal deaths. CONCLUSION: In our study we found that the dengue fever has poor maternal and perinatal outcomes. Measures must be taken to prevent dengue in urban region, and dengue screening during pregnancy must be adopted in endemic regions. 1. World Health Organization (1997) Dengue Hemorrhagic fever: Diagnosis, treatment, prevention and control. 2nd edition. Geneva Available: http://www.who.int/-csr/resources/publications/dengue/Deng uepublication/en/print.html Accessed 2 November 2009. 2. Epidemiology unit of Ministry of Sri Lanka (2010) Dengue in Sri Lanka. Available: http://www.epid.gov.lk/ Dengue_updates.htm. (http://www.-epid.gov.lk/pdf/Dengue/2009/Dhf%20cases%2 0%28H399%29%202010-02-12.pdf) Accessed 15 February 2010. 3. Bharaj P, Chahar HS, Pandey A, Diddi K, Dar L, GuleriaR,Kabra SK, Broor S (2008) Concurrent infections by all four dengue virus serotypes during an outbreak of dengue in 2006 in Delhi. Virol J 9: 1. 4. Gibbons RV and Vaughn DW (2002) Dengue: an escalating problem. BMJ 324: 1563–1566. 5. Carroll ID, Toovey S, Van Gompel A (2007) Dengue fever and pregnancy - a review and comment. Travel Med Infect Dis 5: 183-188. 6. Chotigeat U, Kalayanrooj S, Nisalak A (2003) Vertical transmission of dengue infection in Thai infants: Two case reports. J Med Assoc Thai 86: 628-632. 7. Chye JK, Lim CT, Ng KB, Lim JM, George R, Lam SK (1997) Vertical transmission of dengue. Clin Infect Dis 25:1374-1377. 8. Maroun SL, Marliere RC, Barcellus RC, Barbosa CN, Ramos JR, Moreira ME (2008) Case report: vertical dengue infection. J Pediatr (Rio J) 84: 556-559. 9. Fatimil LE, Mollah AH, Ahmed S, Rahman M (2003) Vertical transmission of dengue: first case report from Bangladesh. Asian J Trop Med Public Health 34: 800-803. 10. Carles G, Peiffer H, Talarmin A: Effects of dengue fever during pregnancy in French Guiana. Clin Infect Dis1999, 28:637–40. 11. 11.Waduge R, Malavige GN, Pradeepan M, Wijeyaratne CN, Fernando S, Seneviratne SL: Dengue infections during pregnancy: a case series from Sri Lanka and review of the literature. J ClinVirol 2006, 37:27–33. 12. Ismail NA, Kampan N, Mahdy ZA, Jamil MA, Razi ZR: Dengue in pregnancy. Southeast Asian J Trop Med Public Health 2006, 37:681–3.25. 13. Carles G, Talarmin A, Peneau C, Bertsch M: Dengue fever and pregnancy. A study of 38 cases in french Guiana [in French]. J GynecolObstetBiolReprod 2000, 29:758–62.26. 14. .Malhotra N, Chanana C, Kumar S: Dengue infection in pregnancy. Int J Gynaecol Obstet 2006, 94:131–2 15. Sharma JB, Gulati N: Potential relationship between dengue fever and neural tube defects in a northern district of India. Int J Gynaecol Obstet 1992, 39:291–5. 16. ,.Watanaveeradej V, Endy TP, Samakoses R, Kerdpanich A, Simasathien S, Polprasert N, Aree C, Vaughn DW, Ho C, Nisalak A: Transplacentally transferred maternal-infant antibodies to dengue virus. Am J Trop Med Hyg2003, 69:123-8. 17. Pouliot SH, Xiong X, Harville E, Paz-Soldan V, Tomashek KM, Breart G, Buekens P: Maternal dengue and pregnancy outcomes: a systematic review. ObstetGynecolSurv 2010, 65:107–18Abstract
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