Title: Rosai Dorfmans Disease: A Rare Benign Disease of Breast
Authors: Dr Akash Kumar Singh, Dr Preeti Jain, Dr Pallavi Agrawal
DOI: http://dx.doi.org/10.18535/jmscr/v4i1.36
Rosai Dorfmans Disease also called sinus histiocytosis with massive lymphadenopathy (SHML) is a rare disorder of sinus histiocyte. Mostly involves lymph nodes but can occur in other body parts. This disease is extremely rare in breast.We report a case of breast lump, clinically & radilogically appearing malignant that found out to be Rosai Dorfmans Disease on histopathology & IHC. 1. Eisen RN,Buckley PJ,and Rosai J.Immunophenotypic charecterisation of sinus histiocytosis with massive lymphad-enopathy (Rosai-Dorfman disease). Semin Diagn pathol. 1990; 7: 74-82 2. Rosai J,Dorfman RF.Sinus histiocytosis with massive lymphadenopathy. Arch pathol 1969,87:63-70 3. Wang KH,Chen WY,Liu HN,et al.Cutaneous Rosai Dorfmans disease: clinicopathological profiles, spectrum and evolution of 21 lesions in six patients.Br J Dermatol 2006; 154:277-286 4. Foucar E,Rosai J and Dorfman R.sinus histiocytosis with massive lymphad-enopathy (Rosai-Dorfmans disease): review of the entity.Semin Diagn Pathol 1990;7: 19-7. 5. Oka M,Kamo T,Goto N,et al.Succesful treatment of Rosai Dorfman disease with low dose steroid.J Dermatol 2009;36237-240Abstract
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